Background And Aims: For young children with intractable epilepsy caused by congenital abnormalities or acquired cortical lesions, pediatric hemispherectomy surgery (pHS) may offer the only path to seizure remediation. Although some sensory and motor outcomes of pHS are highly predictable, the long-term cognitive and functional sequelae of pHS are far more variable. With the aim of identifying potential post-pHS intervention targets, the current study examined daily executive functioning and self-awareness in adults with pHS and broadly intact cognitive outcomes (indicated by average or above performance on intelligence tests).
View Article and Find Full Text PDFObjective: Questions regarding the role of the corpus callosum in attention are raised by the reports of attention problems in some persons with agenesis of the corpus callosum (AgCC), as well as by abnormalities in callosal size in persons with attention-deficit/hyperactive disorder. The current study assessed inattention, impulsivity, and vigilance in individuals with AgCC.
Method: These domains of attention were assessed using the Conners' Continuous Performance Test II in 18 older adolescents and adults (ages 16-52) with complete AgCC and normal intelligence (full scale intelligence quotient > 80).
Background: Environmental enrichment (EE) is a complex living milieu that has been shown to enhance functional recovery versus standard (STD) housing after experimental traumatic brain injury (TBI) and therefore may be considered a rodent correlate of rehabilitation. However, the typical EE paradigm consists of continuous exposure to enrichment after TBI, which is inconsistent with the limited time frame in clinical rehabilitation.
Objective: To determine whether abbreviated EE (ie, rehabilitation-relevant dose response) confers benefits similar to typical EE after TBI.