Publications by authors named "Amanda N Wagner"
Introduction: Pseudobulbar affect, or emotional dysregulation, commonly occurs following stroke. However, it is frequently missed in cases involving the cerebellum, resulting in a lack of treatment, which can directly impact stroke rehabilitation.
Case Presentation: A 63-year-old Caucasian female with no history of mood disorders presented with gait instability, dysarthria, and right sided hemiplegia, secondary to cerebellar and pontine ischemic stroke from a basilar occlusion.
Purpose Of Review: This review aims to summarize the therapeutic advances and evidence in the medical management of acute ischemic stroke (AIS). Recent evidence comparing the efficacy and safety of tenecteplase (TNK) with alteplase for intravenous thrombolysis (IVT) in AIS will be highlighted. Recent advances and evidence on improving micro-circulation following endovascular procedures and neuroprotection will be reviewed.
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- Myasthenia gravis is an autoimmune disease that causes muscle weakness due to autoantibodies targeting the neuromuscular junction, affecting various muscle-related proteins.
- The disease can be categorized based on factors like age of onset, weakness patterns, autoantibody types, and thymic issues, with most patients benefiting from immunosuppressive therapies, though 15% remain difficult to treat.
- Recent advancements in targeted B-cell therapies, including rituximab and eculizumab, have shown promise, though some studies have yielded mixed results, highlighting the need for further research and effective treatments.