Neuroprotective Potential of Flavonoids in Brain Disorders.

Flavonoids are a large subgroup of polyphenols known to be sourced from over 6000 natural products, including fruits, vegetables, bark, and herbs. Due to their antioxidant properties, flavonoids have been implicated as a therapy source for many diseases and conditions, including inflammation, vasculitis, venous insufficiency, and hemorrhoids. Currently, some flavonoids are being researched for their antioxidant ability concerning neuroprotection.

Effect of pre-treatment of strength training and raloxifene in periestropause on bone healing.

Background: There is evidence that strength training (ST) and raloxifene (Ral) treatment during periestropause promotes better bone quality. We wanted to determine whether the skeletal benefits of ST or Ral treatment, performed during periestropause, would persist after fracture. Therefore, the present study aimed to analyze the influence of pre-treatment with ST and administration of Ral during periestropause on bone healing after total unilateral osteotomy.

Intervention for executive functions in attention deficit and hyperactivity disorder.

This study aimed to investigate if an executive functions (EF) intervention could promote these skills in individuals with attention deficit and hyperactivity disorder (ADHD). Eighteen children and adolescents, 7-13 years old, divided into experimental (EG, N = 8) and control (CG, N = 10) groups, were assessed in the Block Design and Vocabulary subtests of the WISC III and seven tests of EF. Parents answered two scales, measuring EF and inattention and hyperactivity signs.

Major peptides from amaranth (Amaranthus cruentus) protein inhibit HMG-CoA reductase activity.

The objective of this study was to identify the major peptides generated by the in vitro hydrolysis of Amaranthus cruentus protein and to verify the effect of these peptides on the activity of 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMG-CoA reductase), a key enzyme in cholesterol biosynthesis. A protein isolate was prepared, and an enzymatic hydrolysis that simulated the in vivo digestion of the protein was performed. After hydrolysis, the peptide mixture was filtered through a 3 kDa membrane.

Age differences in executive functions within a sample of Brazilian children and adolescents.

Executive abilities have been suggested to show differential age-related changes. This study aimed to extend this evidence to a Brazilian sample, which was composed of 572 children and adolescents aged 6 to 14 years, assessed in tests of visual and auditory working memory, selective attention, inhibitory control, cognitive flexibility, attentional abilities, verbal fluency and planning. ANOVAs revealed significant age effect on performance in all tests, with a trend toward better performance with the progression of age, even in differential ways.