Publications by authors named "Amanda Marie Egeskov-Cavling"
Background: Varicella (chickenpox) caused by varicella-zoster virus (VZV) is a highly contagious pediatric disease. While it typically manifests as a mild disease, complications leading to hospitalization are not uncommon. Knowing the current disease burden, seasonality and risk groups is pivotal for evidence-based decisions on the introduction of a varicella vaccine.
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- Respiratory syncytial virus (RSV) is particularly dangerous for older adults and those with other health conditions, and there's limited data on how it affects hospitalized adults in Europe.
- A study analyzing data from March 2016 to April 2020 compared the clinical outcomes of adults hospitalized with RSV or influenza A/B, finding that RSV patients had more comorbidities and higher mortality risks.
- Results showed that hospitalized adults with RSV face increased 90-day mortality, especially compared to those with influenza B, suggesting a need for better testing and vaccination strategies for RSV in older populations.
Background: In light of the substantial impact that respiratory diseases in young children poses on healthcare systems globally, and in the wake of the recent COVID-19 pandemic, there is a growing urgency to obtain reliable estimates on the burden of respiratory disease.
Objectives: The aim of this study is to quantify the overall burden of respiratory disease requiring hospitalizations and explore the trends in these admissions in Danish children <5 years, January 1, 2016-October 31, 2022.
Methods: The number of hospitalizations attributed to respiratory infections in children <5 years, was extracted from the Danish National Patient Register, and stratified into subgroups based on age, gender and birth month, and presented on a month-to-month basis.
Article Synopsis
- The study aimed to estimate the rates of respiratory syncytial virus (RSV)-associated hospitalizations among adults aged 45 and older with various comorbidities in Denmark and Scotland from 2010 to 2018.
- The researchers found that adults with certain comorbidities showed a significantly increased risk of hospitalization due to RSV, with chronic kidney disease and chronic obstructive pulmonary disease being particularly notable.
- The findings highlight the need for targeted vaccination policies for vulnerable groups to reduce the risk of severe RSV infections.
Background: Low awareness and lack of routine testing for respiratory syncytial virus (RSV) infections among adults has led to underreporting in hospital records. This study aimed to assess the underreporting and misclassification of RSV infections among adults hospitalized with an respiratory tract infection (RTI)-coded hospitalization.
Methods: This study is an observational cohort study of RSV-associated hospitalizations among Danish adults (≥18 years old) conducted, between 2015 to 2018.
Background: Worldwide, respiratory syncytial virus (RSV) infections are among the most common causes of infant hospitalization. Host genetic factors influencing the risk and severity of RSV infection are not well known.
Methods: We conducted a genome-wide association study (GWAS) to investigate single-nucleotide polymorphisms (SNPs) associated with severe RSV infections using a nested case-control design based on 2 Danish cohorts.
Background: Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections in adults that can result in hospitalizations. Estimating RSV-associated hospitalization is critical for planning RSV-related healthcare across Europe.
Methods: We gathered RSV-associated hospitalization estimates from the RSV Consortium in Europe (RESCEU) for adults in Denmark, England, Finland, Norway, Netherlands, and Scotland from 2006 to 2017.