Publications by authors named "Amanda Maria de Jesus Bertani"
Article Synopsis
- Antimicrobial resistance is a major public health issue globally, particularly with non-typhoidal Salmonella, which the study investigates through 2,511 isolates collected from 2016 to 2023.
- The study identified 10 common serotypes, with Heidelberg, Typhimurium, and Enteritidis being the most prevalent, and found significant antimicrobial resistance, especially among the Heidelberg and Mbandaka serotypes from nonhuman sources.
- Resistance to several drugs was widespread, although Salmonella Typhi remained mostly susceptible, emphasizing the need for ongoing surveillance and effective public health monitoring.
Article Synopsis
- Public health is increasingly challenged by pathogenic microorganisms with new antimicrobial resistance, making identification difficult for emerging pathogens like NDM-1-producing strains.
- A study documents Brazil's first case of a new ST418 strain, initially misidentified, which was accurately identified through ANI analyses and whole-genome sequencing.
- The study found that the resistance gene was located on a 112 kb IncFIB plasmid, emphasizing the need for public health vigilance as this species may spread significant resistance genes.
Until 2015, polymyxin resistance was primarily attributed to chromosomal mutations. However, with the first report of mobile colistin resistance () in commensal from food animals in China, the landscape has changed. To evaluate the presence of polymyxin resistance in spp.
View Article and Find Full Text PDFDetection and genomic characterization of a multidrug-resistant Salmonella Newport co-harbouring bla, qnrB19 and mcr-9 from the diarrheic faeces of a foal.
J Glob Antimicrob Resist
December 2023
Article Synopsis
- * The research involved various methods like antimicrobial susceptibility testing, whole genome sequencing, and conjugation assays to understand the strain's resistance mechanisms and plasmid characteristics.
- * The findings reveal that strain 195_20 is resistant to multiple antibiotics and carries three significant plasmids related to its resistance genes, highlighting the risk of transmission of these resistant pathogens from animals to humans.
Article Synopsis
- * Whole genome sequencing and antimicrobial susceptibility tests reveal that the isolate (288_18) is resistant to several antibiotics and carries a 67 kb transferable plasmid with the bla gene.
- * The findings stress the need for improved surveillance to control the spread of antibiotic resistance, particularly in clinically relevant strains like Salmonella Agona.
Co-production of Classes A and B Carbapenemases BKC-1 and VIM-2 in a Clinical Pseudomonas Putida Group Isolate from Brazil.
Curr Microbiol
July 2022
Emergence of resistance to classical antimicrobial agents is a public health issue, especially in countries with high antimicrobial consumption rates. Carbapenems have been employed as first-choice option for empirical treatment complicated infections. However, in the last decades, frequency of carbapenemase-producing Gram-negative bacteria has rising, demanding the use of alternative antimicrobial agents.
View Article and Find Full Text PDFArticle Synopsis
- - A patient in Brazil was found to have a multi-drug resistant Salmonella Infantis that produces CTX-M-65.
- - Whole genome sequencing revealed that the antibiotic resistance gene (bla) is located on a pESI-like megaplasmid in this particular strain (ST32).
- - Phylogenetic analysis showed that this Brazilian isolate is closely related to similar IncFIB Salmonella Infantis strains found in food and poultry in the USA.
Genomic and phenotypic characterisation of antimicrobial resistance in carbapenem-resistant Acinetobacter baumannii hyperendemic clones CC1, CC15, CC79 and CC25.
Int J Antimicrob Agents
December 2020
Article Synopsis
- The study investigates the spread of carbapenem-resistant Acinetobacter baumannii (CRAB) in Brazilian hospitals, focusing on specific clonal lineages.
- High rates of CRAB were identified, with predominant clonal complexes including CC1, CC15, CC79, and CC25, and a majority of the isolates exhibiting extensive drug resistance (XDR).
- The research highlights that specific resistance genes are prevalent in these clonal complexes, suggesting that their spread is influenced by antimicrobial resistance mechanisms under selective pressure in healthcare settings.
Genomic and Clinical Characterization of IMP-1-Producing Multidrug-Resistant Isolates from Bloodstream Infections in a Brazilian Tertiary Hospital.
Microb Drug Resist
November 2020
is the main species of the genus; however, non- (NBA) species causing infections have been described for the past years, as well as antimicrobial resistance. In this study, we describe the occurrence of two multidrug-resistant (MDR) IMP-1-producing isolates recovered from bloodstream infections in different patients but in the same intensive care unit among 134 carbapenem-resistant screened. Antimicrobial susceptibility testing revealed resistance to carbapenems, extended spectrum, and antipseudomonad cephalosporins, amikacin, and trimethoprim-sulfamethoxazole.
View Article and Find Full Text PDFMost known plasmids are identified by conferring virulence or antimicrobial resistance phenotypes and such characteristics aid in the success of the dispersion of different plasmid types between bacteria from different sources. This study aimed to perform the subtyping of the plasmid-mediated quinolone resistance, detected in Salmonella spp. A total of 34 Salmonella strains non-susceptible to ciprofloxacin were evaluated.
View Article and Find Full Text PDFMolecular analysis of clonally related Salmonella Typhi recovered from epidemiologically unrelated cases of typhoid fever, Brazil.
Int J Infect Dis
April 2019
Background: The primary method of molecular subtyping for the identification and investigation of outbreaks has been pulsed-field gel electrophoresis (PFGE). In some cases, this technique has not been able to show discrimination between the unrelated strains that can be achieved by whole genome sequencing (WGS).
Methods: The aim of this study was to determine the strengths and drawbacks of WGS using different analytic approaches compared to traditional typing method, PFGE, for retrospectively typing clusters cases of 28 S.