Transvaginal morcellation.

Background And Objectives: Transvaginal uterine morcellation has been described in the literature for more than a century. Despite an extensive body of literature documenting its safety and feasibility, concerns about morcellating occult malignant entities have raised questions regarding this technique. In this study, we looked at a single teaching institution's experience with transvaginal morcellation for leiomyomatous uteri.

A Simple Approach to Specimen Retrieval via Posterior Colpotomy Incision.

Introduction: Posterior colpotomy incision for specimen retrieval is infrequently used in gynecologic laparoscopic surgery unless a concomitant hysterectomy is performed. We aim to describe a simple and unique technique for creating the colpotomy incision and to describe intraoperative and postoperative outcomes.

Methods: Fifty patients underwent adnexal specimen retrieval through a posterior colpotomy incision.

Myomectomy after a vaginal delivery to treat postpartum hemorrhage resulting from an intracavitary leiomyoma.

Background: Postpartum myomectomy is typically discouraged as a result of the risk of hemorrhage and longer operative times. However, myomectomy at the time of cesarean delivery or after a vaginal delivery is feasible and is sometimes necessary.

Case: A 38-year-old multiparous woman with a 9-cm pedunculated submucosal leiomyoma presented in labor and underwent a vacuum-assisted vaginal delivery with manual extraction of the placenta.

A Technique for Vascular Control During Robotic-assisted Laparoscopic Myomectomy.

Study Objective: To show and describe a unique method for improved vascular control when performing a robotic myomectomy.

Design: A video showing skeletonization of the uterine vessels and uterine artery occlusion to maximize vascular control and minimize blood loss during robotic-assisted myomectomy (Canadian Task Force classification III).

Setting: Myomectomy is a procedure often reserved for the treatment of symptomatic leiomyomas in women who desire fertility preservation.

Cesarean scar defects: an underrecognized cause of abnormal uterine bleeding and other gynecologic complications.

The gynecologic sequelae due to deficient uterine scar healing after cesarean section are only recently being identified and described. These include conditions such as abnormal bleeding, pelvic pain, infertility, and cesarean scar ectopic pregnancy, as well as a potentially higher risk of complications and difficulties during gynecologic procedures such as uterine evacuation, hysterectomy, endometrial ablation, and insertion of an intrauterine device. The proposed mechanism of abnormal uterine bleeding is a pouch or "isthmocele" in the lower uterine segment that causes delayed menstrual bleeding.

AFPep, a novel drug for the prevention and treatment of breast cancer, does not disrupt the estrous cycle or fertility in rats.

Pregnancy lowers the risk of breast cancer, largely attributable to alpha-fetoprotein (AFP). A small AFP-derived peptide (AFPep) which mimics the active site of AFP has been developed and may be useful for decreasing the risk of breast cancer for women. AFPep has been shown previously to stop the growth of estrogen-dependent human breast cancer xenografts in mice and prevent carcinogen-induced breast cancer in a rat model.