Prevalence and risk factors of burnout in community pharmacists.

Objectives: This study aimed to identify the prevalence and risk factors for occupational burnout in community pharmacists.

Methods: Community pharmacists were solicited through a professional network e-mail Listserv to complete an anonymous, electronic survey on burnout. The survey included the Maslach Burnout Inventory-Human Services Survey (MBI-HSS) and a work-factors-based questionnaire.

Evidence of burnout in critical care pharmacists.

Purpose: Studies of critical care physicians and nursing personnel indicate a potentially high rate of burnout. To date there is a paucity of data in critical care pharmacists assessing burnout in this group. The purpose of this study was to assess the incidence of risk of burnout in critical care pharmacists.

Evidence of burnout in health-system pharmacists.

Purpose: Results of a study to determine levels of and risk factors for professional burnout among health-system pharmacists are reported.

Methods: The Maslach Burnout Inventory Human Services Survey (MBI-HSS) was distributed to a target population of health-system pharmacists to assess study participants for burnout, which is characterized by feelings of emotional exhaustion, depersonalization, and reduced personal accomplishment. Health-system pharmacists were solicited via email through a professional network listserver to complete an anonymous, electronic questionnaire regarding burnout.

Fungal infection in heart-lung transplant recipients receiving single-agent prophylaxis with itraconazole.

Objectives: Heart and lung transplant recipients are at risk for invasive fungal infections. This study evaluated the affect of single-agent antifungal prophylaxis with itraconazole on the rate of fungal infections after heart or lung transplant.

Materials And Methods: An observational, retrospective study was performed to evaluate the rate of fungal infections in heart and lung transplant recipients at the University of Kentucky Medical Center over 4.

Epileptogenic potential of carbapenem agents: mechanism of action, seizure rates, and clinical considerations.

Antimicrobials are the most frequently implicated class of drugs in drug-induced seizure, with β-lactams being the class of antimicrobials most often implicated. The seizure-inducing potential of the carbapenem subclass may be directly related to their β-lactam ring structure. Data on individual carbapenems and seizure activity are scarce.

Recombinant human erythropoietin therapy in critically ill Jehovah's Witnesses.

Blood transfusions and blood products are often given as a life-saving measure in patients with critical illness. However, some patients, such as Jehovah's Witnesses, may refuse their administration due to religious beliefs. Jehovah's Witnesses accept most available medical treatments, but not blood transfusions or blood products due to their religion's interpretation of several passages from the Bible.

Optimizing transdermal drug therapy.

Purpose: The pharmacokinetics, benefits, risks, and future of transdermal drug products are reviewed.

Summary: Transdermal drug delivery capitalizes on an attractive route of drug delivery, as it avoids the need for painful i.v.

Rhabdomyolysis during therapy with daptomycin.

The use of daptomycin has been associated with an elevation in creatine phosphokinase level, with a reported incidence of 2.8% in phase III clinical trials. Published case reports have documented the presence of myopathy in patients who received daptomycin; however, there have been no previously reported cases of rhabdomyolysis in animals or humans to date.

Postoperative pain management: can transdermal patches help?

While patient-controlled analgesia and intermittent intravenous opioids are primarily used for pain control, transdermal drug delivery is a possible adjuvant treatment.