Acyclic Sesquiterpenes from the Fruit Pericarp of Induce Ultrastructural Alterations and Cell Death in .

Previous studies reported antiprotozoal activities of L. The aim of this work was the evaluation of antileishmanial activity and mechanism of action of extract and fractions of L. Hydroethanolic extract (EHA) obtained from fruit pericarps was fractionated using solid-phase extraction in a reversed phase, resulting in fractions enriched with saponins (SAP fraction) and acyclic sesquiterpene oligoglycosides (OGSA fraction).