Publications by authors named "Amanda Feldpausch"

The extent to which the 2022 mpox outbreak has affected persons without a recent history of male-to-male sexual contact (MMSC) is not well understood. During November 1-December 14, 2022, CDC partnered with six jurisdictional health departments to characterize possible exposures among mpox patients aged ≥18 years who did not report MMSC during the 3 weeks preceding symptom onset. Among 52 patients included in the analysis, 14 (27%) had a known exposure to a person with mpox, including sexual activity and other close intimate contact (eight) and household contact (six).

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  • HIV-related immunosuppression can raise the chances of hospitalization for mpox.
  • In Georgia, a study assessed how HIV status affects hospitalization rates among mpox patients.
  • Individuals with HIV who have a low CD4 count (<350 cells/mm3) or are not receiving HIV treatment are more likely to be hospitalized due to mpox.
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We report 2 cases of pharyngeal monkeypox virus and group A Streptococcus co-infection in the United States. No rash was observed when pharyngitis symptoms began. One patient required intubation before mpox was diagnosed.

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As of March 7, 2023, a total of 30,235 confirmed and probable monkeypox (mpox) cases were reported in the United States, predominantly among cisgender men who reported recent sexual contact with another man (1). Although most mpox cases during the current outbreak have been self-limited, cases of severe illness and death have been reported (2-4). During May 10, 2022-March 7, 2023, 38 deaths among persons with probable or confirmed mpox (1.

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Monkeypox (mpox) cases in the 2022 outbreak have primarily occurred among adult gay, bisexual, and other men who have sex with men (MSM); however, other populations have also been affected (1). To date, data on mpox in cisgender women and pregnant persons have been limited. Understanding transmission in these populations is critical for mpox prevention.

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Data on monkeypox in children and adolescents aged <18 years are limited (1,2). During May 17–September 24, 2022, a total of 25,038 monkeypox cases were reported in the United States, primarily among adult gay, bisexual, and other men who have sex with men (3). During this period, CDC and U.

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  • * A CDC report analyzed 57 hospitalized monkeypox patients from August to October 2022, revealing that 82% had HIV, most were male (95%), and 68% were non-Hispanic Black; 30% needed ICU care, and 21% died due to severe symptoms.
  • * Health care providers are advised to test sexually active monkeypox patients for HIV and consider aggressive treatment for those who are severely immunocompromised
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  • - Monkeypox, which originates from an orthopoxvirus and is commonly found in Africa, has led to a public health emergency in the U.S. since its outbreak began in May 2022, with over 2,891 cases reported by late July 2022.
  • - The majority of cases (99%) are among men, with a high correlation to male-to-male sexual or intimate contact, and there are significant disparities among racial and ethnic groups, particularly among non-Hispanic White, Hispanic, and Black populations.
  • - The CDC and health agencies are focusing their response on enhancing testing, treatment, and vaccination, particularly for gay and bisexual men who are significantly impacted, while emphasizing the importance of equity and
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On May 17, 2022, the Massachusetts Department of Public Health (MDPH) Laboratory Response Network (LRN) laboratory confirmed the presence of orthopoxvirus DNA via real-time polymerase chain reaction (PCR) from lesion swabs obtained from a Massachusetts resident. Orthopoxviruses include Monkeypox virus, the causative agent of monkeypox. Subsequent real-time PCR testing at CDC on May 18 confirmed that the patient was infected with the West African clade of Monkeypox virus.

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  • - SARS-CoV-2 has been found in various species, including pets like dogs and cats, with dog illnesses typically resolving on their own without extensive diagnosis.
  • - As new variants of SARS-CoV-2 arise, the symptoms and transmission dynamics in animals can change, prompting a need for ongoing monitoring.
  • - The report focuses on two dogs infected with the Delta variant, showing different symptoms despite similar exposure to a vaccinated human, underlining the necessity for more research on the impact of these variants on pets and other animals.
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  • Monkeypox is a rare zoonotic infection mainly found in west and central Africa, caused by the Monkeypox virus, which is related to the smallpox virus.
  • After nearly four decades without cases in Nigeria, a significant outbreak occurred between 2017-2018, resulting in 118 confirmed infections, followed by sporadic cases, including six diagnoses in non-African countries between 2018 and 2021.
  • In July 2021, a traveler from Nigeria to Texas was diagnosed with monkeypox, with 74% of monitored contacts being flight contacts; the patient was treated with an antiviral and required decontamination, but the exact source of the infection remains unidentified.
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Human-to-animal and animal-to-animal transmission of SARS-CoV-2 has been documented; however, investigations into SARS-CoV-2 transmission in congregate animal settings are lacking. We investigated four animal shelters in the United States that had identified animals with exposure to shelter employees with laboratory-confirmed COVID-19. Of the 96 cats and dogs with specimens collected, only one dog had detectable SARS-CoV-2 neutralizing antibodies; no animal specimens had detectable viral RNA.

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We describe coronavirus disease (COVID-19) among US food manufacturing and agriculture workers and provide updated information on meat and poultry processing workers. Among 742 food and agriculture workplaces in 30 states, 8,978 workers had confirmed COVID-19; 55 workers died. Racial and ethnic minority workers could be disproportionately affected by COVID-19.

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Meat and poultry processing facilities face distinctive challenges in the control of infectious diseases, including coronavirus disease 2019 (COVID-19) (1). COVID-19 outbreaks among meat and poultry processing facility workers can rapidly affect large numbers of persons. Assessment of COVID-19 cases among workers in 115 meat and poultry processing facilities through April 27, 2020, documented 4,913 cases and 20 deaths reported by 19 states (1).

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Background: There is an urgent need for studies of viral persistence and immunity during human Zika infections to inform planning and conduct of vaccine clinical trials.

Methods: In 5 returned US travelers with acute symptomatic Zika infection, clinical features, viral RNA levels, and immune responses were characterized.

Results: Two pregnant, flavivirus-experienced patients had viral RNA persist in plasma for >44 and >26 days.

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During 2012-2014, five cases of Rickettsia parkeri rickettsiosis were identified by a single urgent care practice in Georgia, located approximately 40 miles southwest of Atlanta. Symptom onset occurred during June-October, and all patients had a known tick bite. Patients ranged in age from 27 to 72 years (median = 53 years), and all were male.

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Since April 1, 2015, a total of 11 cases of human plague have been reported in residents of six states: Arizona (two), California (one), Colorado (four), Georgia (one), New Mexico (two), and Oregon (one). The two cases in Georgia and California residents have been linked to exposures at or near Yosemite National Park in the southern Sierra Nevada Mountains of California. Nine of the 11 patients were male; median age was 52 years (range = 14-79 years).

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The Ebola virus disease (Ebola) epidemic in West Africa has so far produced approximately 25,000 cases, more than 40 times the number in any previously documented Ebola outbreak. Because of the risk for imported disease from infected travelers, in October 2014 CDC recommended that all travelers to the United States from Ebola-affected countries receive enhanced entry screening and postarrival active monitoring for Ebola signs or symptoms until 21 days after their departure from an Ebola-affected country. The state of Georgia began its active monitoring program on October 25, 2014.

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