Publications by authors named "Amanda E Nwokeji"
Endothelial Cell Regulates Neurovascular, Neuronal, and Behavioral Function.
Felecia M Marottoli Hui Zhang Eden Flores-Barrera Emilce Artur de la Villarmois Frederick C Damen Amanda E Nwokeji
Arterioscler Thromb Vasc Biol
October 2023
Background: Specialized brain endothelial cells and human are independently important for neurovascular function, yet whether expression by endothelial cells contributes to brain function is currently unknown. In the present study, we determined whether the loss of endothelial cell impacts brain vascular and neural function.
Methods: We developed /Cdh5(PAC)-CreERT2 () and /Cdh5(PAC)-CreERT2 (, control) mice and induced endothelial cell knockdown with tamoxifen at ≈4 to 5 weeks of age.