Moderate physical activity from childhood contributes to metabolic health and reduces hepatic fat accumulation in adult rats.

Background: Obesity, oxidative stress and inflammation, by triggering insulin resistance, may contribute to the accumulation of hepatic fat, and this accumulation by lipotoxicity can lead the organ to fail. Because obesity is growing at an alarming rate and, worryingly, in a precocious way, the present study aimed to investigate the effects of moderate physical training performed from childhood to adulthood on liver fat metabolism in rats.

Methods: Twenty rats that were 28 days old were divided into two groups: control (C) and trained (T).

Effects of physical training with different intensities of effort on lipid metabolism in rats submitted to the neonatal application of alloxan.

Background: Type 2 diabetes mellitus (T2DM) is a chronic disease that is characterized by insulin resistance. Its development is directly connected with the inability of insulin to exert its action, not just on carbohydrate metabolism but also on primarily on lipid metabolism. The present study aimed to compare the effects of continuous, intermittent, and strength training on serum and tissue variables on the lipid metabolism of alloxan rats.