Synthesis, structure, and reactivity of a nickel dihydrogen complex.

Hydrogen activation by nickel: A tBuPCP pincer ligand facilitates formation of cationic Ni(II) dihydrogen and terminal dinitrogen complexes. The compounds have been characterized by X-ray crystallography and NMR spectroscopy. Addition of base promotes heterolytic cleavage of H(2) to form the corresponding neutral hydride complex.

Age-dependent reference intervals for measured bioavailable testosterone on the Siemens Advia Centaur: ethnicity-specific values not necessary for South Asians.

Objectives: To determine reference intervals for bioavailable testosterone for the Siemens Centaur analyzer and to assess the need for ethnicity-specific ranges for total testosterone and/or bioavailable testosterone in South Asians.

Design And Methods: Testosterone was measured before and after ammonium sulphate precipitation on specimens collected from a small cohort of healthy male South Asians and Europeans.

Results: Inter-ethnicity differences in BioT and TT were not significant.

Spurious hyperbilirubinemia caused by naproxen.

Objective: To confirm that the naproxen metabolite O-desmethylnaproxen interferes with the Jendrassik and Grof method for total bilirubin and was a possible cause of spurious hyperbilirubinemia in a case of naproxen overdose.

Design And Methods: Plasma was spiked with naproxen or O-desmethylnaproxen before total and direct bilirubin analysis.

Results: O-desmethylnaproxen concentration showed a linear relationship with measured total bilirubin.