Publications by authors named "Amanda C Schoeffel"
Article Synopsis
- The study focused on creating and testing chlorhexidine:β-cyclodextrin (Chx:βCD) complexes for their antifungal properties.
- Physicochemical analysis showed that a 1:2 molar ratio of Chx:βCD was optimal for achieving antifungal activity against nine different fungal strains.
- When added to denture material, Chx:βCD demonstrated enhanced antifungal effectiveness, needing only 7.5% of Chx concentration to remain effective for 14 days, suggesting potential for new treatments for oral candidiasis and denture stomatitis.
Background: Nystatin (Nys) is a fungicidal drug commonly prescribed for candidiasis disease in several administration routes. However, Nys is a class IV drug, according to the Biopharmaceutical Classification System, that possesses limited bioavailability and is used for local activity.
Objective: This study developed and characterized nystatin:β-cyclodextrin (Nys:βCD) inclusion complexes and evaluated their activity against spp.
Background: Microwave polymerization reduces the time of acrylic resin processing, but it is important to select a proper cycle to avoid overheating, porosity, and impairment to the materials' properties.
Aims: To evaluate the microhardness of conventional (Vipi Cril-VC) and microwaved (Vipi Wave-VW) acrylic resins after microwave polymerization cycles and the cycles recommended by the manufacturer. It was also evaluated the effect of thermocycling on the microhardness of these materials.
The effect of polymerization cycles on flexural properties of conventional (Vipi Cril(®)-VC) or microwave-processed (Vipi Wave(®)-VW) denture base acrylic resins was evaluated. Specimens (n=10) were submitted to the cycles: WB=65ºC for 1 h+1 h boiling water (VC cycle); M630/25=10 min at 270 W+5 min at 0 W+10 min at 360 W (VW cycle); M650/5=5 min at 650 W; M700/4=4 min at 700 W; and M550/3=3 min at 550 W. Specimens were submitted to a three-point bending test at 5 mm/min until fracture.
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