Condensed Layer Deposition of Nanoscopic TiO Overlayers on High-Surface-Area Electrocatalysts.

Encapsulating an electrocatalytic material with a semipermeable, nanoscopic oxide overlayer offers a promising approach to enhancing its stability, activity, and/or selectivity compared to an unencapsulated electrocatalyst. However, applying nanoscopic oxide encapsulation layers to high-surface-area electrodes such as nanoparticle-supported porous electrodes is a challenging task. This study demonstrates that the recently developed condensed layer deposition (CLD) method can be used for depositing nanoscopic (sub-10 nm thick) titanium dioxide (TiO) overlayers onto high-surface-area platinized carbon foam electrodes.

Protonation of CH N and CF N in Superacids: Isolation and Structural Characterization of Long-Lived Methyl- and Trifluoromethylamino Diazonium Ions.

The methylamino diazonium cations [CH N(H)N ] and [CF N(H)N ] were prepared as their low-temperature stable [AsF ] salts by protonation of azidomethane and azidotrifluoromethane in superacidic systems. They were characterized by NMR and Raman spectroscopy. Unequivocal proof of the protonation site was obtained by the crystal structures of both salts, confirming the formation of alkylamino diazonium ions.

Review of services to inform clinical frameworks for adolescents and young adults with severe, persistent and complex mental illness.

Objective: Severe, persistent and complex mental illness (SPCMI) affects a small proportion of young people but is associated with severe disability and a large burden on families and health services. This article identifies and describes service models for adolescents and young adults with SPCMI.

Methods: A systematic search was conducted for services for young people aged 12-25 years with SPCMI.

Formamidinium Nitroformate: An Insensitive RDX Alternative.

Five nitroformate (trinitromethanide) salts featuring nitrogen-containing cations were prepared. The salts were characterized by multinuclear NMR, IR, and Raman spectroscopy, single-crystal X-ray analysis, differential thermal analysis, and friction and impact sensitivity testing. These experimental data are supplemented with thermochemical calculations using the Gaussian-4 composite method, and the performance of these energetic materials was calculated based on the Chapman-Jouguet thermodynamic detonation theory.

α-Fluoroalcohols: Synthesis and Characterization of Perfluorinated Methanol, Ethanol and n-Propanol, and their Oxonium Salts.

The thermally unstable, primary perfluoroalcohols, CF OH, C F OH, and nC F OH, were conveniently prepared from the corresponding carbonyl compounds in anhydrous HF solution. Experimental values for the reaction enthalpies and entropies were derived from the temperature dependence of the R COF+HF⇄R CF OH (R =F, CF , CF CF ) equilibria by NMR spectroscopy. Electronic structure calculations of the gas-phase and solution reaction energies, gas-phase acidities and heats of formation were carried out at the G3MP2 level, showing that these compounds are strong acids.

Increased mortality among people with schizophrenia and other non-affective psychotic disorders in the community: A systematic review and meta-analysis.

Introduction: There is increasing evidence of excess mortality in schizophrenia but less information on other non-affective psychoses. We therefore generated standardised mortality ratios (SMRs) for community-dwelling people with schizophrenia and other non-affective psychoses, relative to the general population, and examined changes to the SMR over time.

Methods: We conducted a systematic review in which Pubmed, CINAHL, EMBASE, Google Scholar and PsycINFO were searched for publications that reported SMRs for all-cause mortality among community-dwelling people with schizophrenia and psychotic disorders.

Perfluoroalcohols: The Preparation and Crystal Structures of Heptafluorocyclobutanol and Hexafluorocyclobutane-1,1-diol.

The first X-ray crystal structure of an α-fluoroalcohol is reported. Heptafluorocyclobutanol was obtained in quantitative yield from hexafluorocyclobutanone by HF addition in anhydrous hydrogen fluoride. The compound was characterized by its X-ray single crystal structure.

Identifying characteristics and practices of multidisciplinary team reviews for patients with severe mental illness: a systematic review.

Objectives: Multidisciplinary teams in mental health receive limited guidance, leading to inconsistent practices. We undertook a systematic review of the characteristics and practices of multidisciplinary team reviews for patients with severe mental illness or in relevant mental health service settings.

Methods: Sources published since 2000 were located via academic database and web searches.

Assessing service use for mental health by Indigenous populations in Australia, Canada, New Zealand and the United States of America: a rapid review of population surveys.

Background: Indigenous people in Australia, Canada, New Zealand and the United States of America experience disproportionately poor mental health compared to their non-Indigenous counterparts. To optimally allocate resources, health planners require information about the services Indigenous people use for mental health, their unmet treatment needs and the barriers to care. We reviewed population surveys of Indigenous people to determine whether the information needed to guide service development is being collected.

Systematic review of interventions for Indigenous adults with mental and substance use disorders in Australia, Canada, New Zealand and the United States.

Objective: The aim of this study was to systematically review the evidence-base for the effectiveness of culturally unadapted, culturally adapted and culture-based interventions for Indigenous adults with mental or substance use disorders.

Methods: We conducted a systematic search of scientific databases, government websites and web-based Indigenous research repositories. We sought studies using designs comparing an intervention group to a control/comparator group or pre- and post-test designs, published between 2000 and 2015 examining interventions to improve individual-level outcomes (e.

In an open publishing house not so far, far away….

Summary: As completes its first circle around the sun and marks its first anniversary, we share with you its strengths and advantages that underpin its success as a new journal. First and foremost, the editorial team has maintained rigorous scientific standards while pursuing an open access publishing model that, by design, accommodates a broad range of clinical and scientific topics. Fundamental to 's mission has been our policy of accepting papers that are both methodologically sound and intellectually stimulating.

Social correlates of mental, neurological, and substance use disorders in China and India: a review.

Understanding the epidemiological profiles of mental, neurological, and substance use disorders provides opportunities for the identification of high-risk population subgroups and for the development of effective country-specific prevention and intervention strategies. Guided by the Conceptual Framework for Action on the Social Determinants of Health by WHO we reviewed the literature to examine the association between a range of social correlates (eg, sex, age, education, income, urbanicity, marital status, and regional differences) and mental, neurological, and substance use disorders in China and India, the most populous countries in the world. We looked for papers on mental, neurological, and substance use disorders with location identifiers and socioeconomic correlates published between 1990 and 2015 and our search found 65 relevant studies from China and 29 from India.

Prevalence of mental, neurological, and substance use disorders in China and India: a systematic analysis.

Background: Population-representative prevalence data for mental, neurological, and substance use disorders are essential for evidence-based decision making. As a background to the China-India Mental Health Alliance Series, we aim to examine the availability of data and report prevalence for the most common mental, neurological, and substance use disorders in China and India from the Global Burden of Disease study 2013 (GBD 2013).

Methods: In this systematic analysis, data sources were identified from GBD 2013 for the prevalence of mental, neurological, and substance use disorders in China and India published up to Dec 31, 2013.

The burden of mental, neurological, and substance use disorders in China and India: a systematic analysis of community representative epidemiological studies.

Background: China and India jointly account for 38% of the world population, so understanding the burden attributed to mental, neurological, and substance use disorders within these two countries is essential. As part of the Lancet/Lancet Psychiatry China-India Mental Health Alliance Series, we aim to provide estimates of the burden of mental, neurological, and substance use disorders for China and India from the Global Burden of Disease Study 2013 (GBD 2013).

Methods: In this systematic analysis for community representative epidemiological studies, we conducted systematic reviews in line with PRISMA guidelines for community representative epidemiological studies.

Protonation of nitriles: isolation and characterization of alkyl- and arylnitrilium ions.

The reactions of acetonitrile, propionitrile, butyronitrile, N,N-dimethylaminoacetonitrile, benzonitrile, o-tolunitrile and 1,4-dicyanobenzene with HF/AsF5 or HF/SbF5 in anhydrous HF result in protonation of the nitrile. The obtained nitrilium ions were isolated as [AsF6](-), [SbF6](-) and [Sb2F11](-) salts and characterized by multinuclear NMR and vibrational spectroscopy, and their X-ray crystal structures.

Reducing excess mortality due to chronic disease in people with severe mental illness: meta-review of health interventions.

Background: People with severe mental illness (SMI) have high rates of chronic disease and premature death.

Aims: To explore the strength of evidence for interventions to reduce risk of mortality in people with SMI.

Method: In a meta-review of 16 systematic reviews of controlled studies, mortality was the primary outcome (8 reviews).

Convenient Access to α-Fluorinated Alkylammonium Salts.

A series of novel α-fluoroalkyl ammonium salts was obtained from the corresponding cyano compounds or nitriles by reaction with anhydrous HF. Room-temperature stable trifluoromethyl ammonium salts were obtained in quantitative yield in a one-step reaction at ambient temperature from the commercially available starting materials BrCN or ClCN. The novel cations [CF3CF2NH3](+), [HCF2CF2NH3](+), and [(NH3CF2)2](2+) were obtained from CF3CN, HCF2CN, and (CN)2, respectively, and anhydrous HF.

Males' mental health disadvantage: An estimation of gender-specific changes in service utilisation for mental and substance use disorders in Australia.

Background: Concerns about low levels of service utilisation for mental and substance use disorders in Australia - especially among males - have prompted targeted help-seeking and stigma-reduction initiatives. Resulting changes in service utilisation according to gender are unknown. We modelled the percentage of Australian males with a mental or substance use disorder who used services each year between 2006-2007 and 2011-2012, and the types of services they used, relative to females.

Pulsed magnetic field induced fast drug release from magneto liposomes via ultrasound generation.

Fast drug delivery is very important to utilize drug molecules that are short-lived under physiological conditions. Techniques that can release model molecules under physiological conditions could play an important role to discover the pharmacokinetics of short-lived substances in the body. Here an experimental method is developed for the fast release of the liposomes' payload without a significant increase in (local) temperatures.

The regional distribution of anxiety disorders: implications for the Global Burden of Disease Study, 2010.

Anxiety disorders are increasingly acknowledged as a global health issue however an accurate picture of prevalence across populations is lacking. Empirical data are incomplete and inconsistent so alternate means of estimating prevalence are required to inform estimates for the new Global Burden of Disease Study 2010. We used a Bayesian meta-regression approach which included empirical epidemiological data, expert prior information, study covariates and population characteristics.

The global epidemiology and burden of psychostimulant dependence: findings from the Global Burden of Disease Study 2010.

Aims: To estimate the global prevalence of cocaine and amphetamine dependence and the burden of disease attributable to these disorders.

Methods: An epidemiological model was developed using DisMod-MR, a Bayesian meta-regression tool, using epidemiological data (prevalence, incidence, remission and mortality) sourced from a multi-stage systematic review of data. Age, sex and region-specific prevalence was estimated for and multiplied by comorbidity-adjusted disability weightings to estimate years of life lost to disability (YLDs) from these disorders.

Challenging the myth of an "epidemic" of common mental disorders: trends in the global prevalence of anxiety and depression between 1990 and 2010.

Background: Anxiety disorders and major depressive disorder (MDD) are common and disabling mental disorders. This paper aims to test the hypothesis that common mental disorders have become more prevalent over the past two decades.

Methods: We conducted a systematic review of prevalence, remission, duration, and excess mortality studies for anxiety disorders and MDD and then used a Bayesian meta-regression approach to estimate point prevalence for 1990, 2005, and 2010.

The contribution of major depression to the global burden of ischemic heart disease: a comparative risk assessment.

Background: Cardiovascular disease and mental health both hold enormous public health importance, both ranking highly in results of the recent Global Burden of Disease Study 2010 (GBD 2010). For the first time, the GBD 2010 has systematically and quantitatively assessed major depression as an independent risk factor for the development of ischemic heart disease (IHD) using comparative risk assessment methodology.

Methods: A pooled relative risk (RR) was calculated from studies identified through a systematic review with strict inclusion criteria designed to provide evidence of independent risk factor status.