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Publications by authors named "Amanda Antunes Herling"

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Adult and pediatric physiologically-based biopharmaceutics modeling to explain lamotrigine immediate release absorption process.
Edilainy Rizzieri Caleffi-Marchesini Amanda Antunes Herling Julia Macente Rodolfo Hernandes Bonan Priscila de Freitas Lima

CPT Pharmacometrics Syst Pharmacol

February 2024

Physiologically-based biopharmaceutics modeling (PBBM) has potential to accelerate the development of new drug and formulations. An important application of PBBM is for special populations such as pediatrics that have pharmacokinetics dependent on the maturation process. Lamotrigine (LTG) is a Biopharmaceutics Classification System (BCS) II drug and is widely prescribed.

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