Influence of total intravenous anesthesia, entropy and laparoscopy on oxidative stress.

Background And Objectives: Recent studies have correlated postoperative mortality with anesthetic mortality, especially with the depth of anesthesia and systolic blood pressure (SBP). The aim of this study is to evaluate the effects of the depth of total intravenous anesthesia (TIVA) using remifentanil and propofol, performed with monitoring of response entropy (RE) on blood concentrations of oxidative stress markers (TBARS and glutathione) during laparoscopic operations.

Method: Twenty adult patients, ASA I, BMI 20-26 kg.