Deltamethrin, a pyrethroid insecticide, could be a promising candidate as an anticancer agent.

Cancer is the one of the leading causes of death, whose incidences is increasing day by day. Various types of anticancer agents are used for its treatment, but unfortunately none of them is able to treat the cancer. Thus, the exploration of novel mechanistic pathways of existing molecules may help to develop more effective anticancer agents.

Deltamethrin-induced oxidative stress and mitochondrial caspase-dependent signaling pathways in murine splenocytes.

Deltamethrin (DLM) is a well-known pyrethroid insecticide used extensively in pest control. Exposure to DLM has been demonstrated to cause apoptosis in various cells. However, the immunotoxic effects of DLM on mammalian system and its mechanism is still an open question to be explored.