Incidence and Risk Factors for Hypertension among Children with Nephrotic Syndrome.

Objectives: To determine incidence and risk factors for hypertension in childhood nephrotic syndrome.

Study Design: Using data from the Insight into Nephrotic Syndrome (INSIGHT) study, a prospective observational childhood nephrotic syndrome cohort from Toronto, Canada, we evaluated hypertension incidence and time-to-hypertension overall and stratified by 1) steroid-resistance or steroid-sensitivity, and 2) frequently-relapsing, steroid dependent, or infrequently-relapsing. Hypertension was defined as stage 1-2 hypertensive blood pressure on two consecutive visits or anti-hypertensive medication initiation.

Prolonged remission after cyclophosphamide or tacrolimus treatment in childhood nephrotic syndrome: a cohort study.

Background: Steroid-sparing immunosuppression is used in 50% of children with nephrotic syndrome, to prevent relapses and steroid-related toxicity. However, rates and predictors of prolonged remission after cyclophosphamide and tacrolimus are uncertain.

Methods: Retrospective analysis of children (1-18 years) enrolled in a longitudinal cohort.

Estimating visibility and understanding factors influencing its variations at Bangkok airport using machine learning and a game theory-based approach.

In this study, six individual machine learning (ML) models and a stacked ensemble model (SEM) were used for daytime visibility estimation at Bangkok airport during the dry season (November-April) for 2017-2022. The individual ML models are random forest, adaptive boosting, gradient boosting, extreme gradient boosting, light gradient boosting machine, and cat boosting. The SEM was developed by the combination of outputs from the individual models.

Development of Acceptable Quality Dose (AQD) and image quality-related diagnostic reference levels for common computed tomography investigations in a tertiary care public sector hospital of Khyber Pakhtunkhwa, Pakistan.

Purpose: To describe the first experience of patient dose optimization in developing AQD, SSDE and image quality-related DRLs for common CT examinations in the adult age group using the concept of AQD.

Materials And Methods: The recent published IQSC from 0 to 4 were used by radiologists for the assessment of image quality. The entire data were collected for five types (brain CT, chest CT, chest HRCT, abdomen KUB CT and abdomen + pelvic CT) CT investigations based on anatomic region (head, chest and abdomen + pelvic).

Colonic lymphomatous polyposis mantle cell lymphoma: a case report and review of literature.

Introduction: Mantle cell lymphoma is a rare lymphoma of the gastrointestinal tract that may present as multiple lymphomatous polyposis. We report a case of lymphomatous polyposis with a review of the literature.

Case Report: A 56-year-old man of Black ethnicity and Ivorian nationality with no relevant past medical history, consulted for a sudden onset symptoms of gastrointestinal obstruction, which evolved over 2 days.

Sustaining the Earth: Unraveling the Synergy of Workplace Spirituality, Responsible Leadership, and Pro-Environmental Behavior in Pakistan's SMEs.

Purpose: The purpose of this research is to investigate the synergistic impact of workplace spirituality (WPS), responsible leadership (RL), and pro-environmental behavior (PEB) within the context of Pakistan's Small and Medium Enterprises (SMEs) along with the mediating mechanism of Affective commitment (AC).

Methods: Our study utilizes structural equation modeling (SEM) to analyze survey data collected from 390 employees within Pakistani SMEs. We develop a single unified framework to test the hypothesized relationships between RL, PEB, and AC as a mediator.

A Study of Urban Haze and Its Association with Cold Surge and Sea Breeze for Greater Bangkok.

This study deals with haze characteristics under the influence of the cold surge and sea breeze for Greater Bangkok (GBK) in 2017-2022, including haze intensity and duration, meteorological classification for haze, and the potential effects of secondary aerosols and biomass burning. A total of 38 haze episodes and 159 haze days were identified. The episode duration varies from a single day to up to 14 days, suggesting different pathways of its formation and evolution.

A compendium of macrofungi of Pakistan by ecoregions.

Macrofungi form fruiting bodies that can be detected with the naked eye in the field and handled by hand. They mostly consist of basidiomycetes, but also include some ascomycetes. Mycology in Pakistan is still in its infancy, but there have been many historical reports and checklists of macrofungi occurrence from its 15 ecoregions, which range from Himalayan alpine grasslands and subtropical pine forests to deserts and xeric shrublands.

Perceived corporate social responsibility, ethical leadership, and moral reflectiveness impact on pro-environmental behavior among employees of small and medium enterprises: A double-mediation model.

Corporate social responsibility (CSR) is ever-evolving concept and gaining significance in the business world. This research proposes a research model that elucidates the mechanism by which Corporate social responsibility (CSR), ethical leadership, and moral reflectiveness promote pro-environmental behavior among employees of Small and Medium Enterprises (SMEs). In today's ever-changing environment, small and medium companies (SMEs) are critical for any economy to thrive and prosper.

Family functioning and quality of life among children with nephrotic syndrome during the first pandemic wave.

Background: During the SARS-CoV-2 global pandemic, one of the longest lockdowns worldwide occurred in Ontario, Canada, during the first wave. For parents and children managing care at home and at risk for COVID-19, the impact on their psychosocial functioning is unknown.

Methods: A total of 122 families of children aged 2-18 years were enrolled as part of the prospective cohort of childhood nephrotic syndrome and completed a survey during the first wave of the pandemic (August 21-December 10), 2020.

Policy Intervention and Financial Sustainability in an Emerging Economy: A Structural Vector Auto Regression Analysis.

The purpose of the study is to observe the impact of policy intervention on financial sustainability using the structural vector autoregression (SVAR) analysis. The population of the study is the manufacturing sector of Pakistan, which is an emerging economy. Data for 249 firms operating in the manufacturing sector are taken, collected from Datastream from 2005 to 2019, with total observations of 2,400.

Visibility, aerosol optical depth, and low-visibility events in Bangkok during the dry season and associated local weather and synoptic patterns.

Visibility and aerosol optical depth (AOD) characterization, and their relationship with PM and local and synoptic meteorology, were studied for January-March in 2014 and 2015 over Bangkok. Visibility degradation intensifies in the dry season as compared to the wet season due to increase in PM and unfavorable meteorological conditions. The average visibility is lower in January and February as compared to the other months.

The effects of touch-screen technology usage on hand skills among preschool children: a case-control study.

Little is known on how time spent on touch-screen technology affects the hand skills development of preschool children. This study aimed to investigate the effects of touch-screen technology usage on hand skills among preschool children. Case-control design was employed to compare the hand skills of children who were engaged in touch-screen technology.

Quality of life and life satisfaction among university students: Exploring, subjective norms, general health, optimism, and attitude as potential mediators.

Objective: This study aims to examine the association of quality of life (QOL) with life satisfaction, subjective norms, general health, optimism, and attitude among university students.

Participants: Respondents include 632 university students (M=21.36, SD = 2.

Evolution of Urban Haze in Greater Bangkok and Association with Local Meteorological and Synoptic Characteristics during Two Recent Haze Episodes.

This present work investigates several local and synoptic meteorological aspects associated with two wintertime haze episodes in Greater Bangkok using observational data, covering synoptic patterns evolution, day-to-day and diurnal variation, dynamic stability, temperature inversion, and back-trajectories. The episodes include an elevated haze event of 16 days (14-29 January 2015) for the first episode and 8 days (19-26 December 2017) for the second episode, together with some days before and after the haze event. Daily PM was found to be 50 µg m or higher over most of the days during both haze events.

Synthesis and Biological Evaluation of Amoxicillin Loaded Hybrid Material Composite Spheres Against Methicillin-Resistant Staphylococcus aureus.

Background: Incoherent use of antibiotics has led toward resistance in MRSA, becoming multidrug-resistant with a high rate of virulence in the community and hospital settings.

Objective: Synergistic anti-MRSA activity was investigated in this study for hybrid material composite spheres of amoxicillin, Ag nanoparticles, and chitosan, which were prepared by one-step synthesis method, and various characterizations were performed.

Methods: Antimicrobial-susceptibility assay on MRSA was achieved by disc diffusion and agar dilution techniques, while agar well diffusion was used for hybrid composite spheres.

Effects of touch-screen technology usage on the hand skills dataset.

This data article describes the hand skills of pre-school children between five and six years old from five schools under the Ministry of Education Malaysia. These data may be used in a journal article later to show the effects of touch-screen technology usage on hand skills of pre-school children. Demographic characteristics, hand skills ability and frequency of touch-screen technology usage data that was collected from August to September 2019.

Comparative Fluoride Release and Antimicrobial Analysis of Commercial and Experimental Bioactive Glass/Nano-Oxide-Based Dentifrices.

Objectives:  The objectives were to measure fluoride release and assess the antimicrobial behavior of fluoride-doped nano bioactive glass (F-nBG) and nano zinc oxide (ZnO)-enriched novel dentifrices.

Materials And Methods:  Experimental dentifrices were synthesized by incorporating ZnO nanoparticles and F-nBG (1.5 wt% and 4 wt%) as active ingredients.

Effect of commercial and green synthesized ZnO NPs in murine model of chloroquine-induced pruritus.

To investigate the effects of zinc oxide nanoparticles (ZnO NPs) on chloroquine (CQ)-induced itching, and overall behavior of mice after oral administration of ZnO NPs of various sizes and doses. With the wide-spread use of ZnO NPs in pharmaceuticals and cosmetics, concerns about their safety and toxicity are also increasing. Multiple aspects of ZnO NPs regarding cytotoxicity and tolerability are under investigation globally.

Immunohistochemical Evaluation of Ki-67 and Comparison with Clinicopathologic Factors in Breast Carcinomas.

Background: Patients primarily received tamoxifen based on their menopausal status due to the lack of immunohistochemistry. A recent study has shown that hormonal receptors were not correlated with menopausal status, and thus, indicating that they present limited therapeutic and prognostic significance in breast cancer management. This study aimed to evaluate Ki-67 value and analyze its association with clinicopathologic parameters in breast cancer patients.

HER2 overexpression and correlation with other significant clinicopathologic parameters in Ivorian breast cancer women.

Background: The overexpression of HER2 is associated with worse prognosis of breast cancer which responds favourably to anti-HER2 therapy. The objective of this study was to determine the frequency of HER2 and its association with clinicopathologic factors in breast cancer in Ivory Coast.

Methods: The study included 608 patients who were histologically diagnosed with invasive primary breast carcinoma.

Design, Formulation and Evaluation of Sustained-release Tablet Formulations of Levosulpiride.

Objectives: Levosulpiride is a widely used gastroprokinetic agent in the treatment of various gastric disorders; however, its short half-life and increased dosage frequency leads to non-compliance and possible adverse effects. The prime objective of the current study was to develop a sustained-release formulation of Levosulpiride incorporating bioresorbable cellulose derivatives.

Materials And Methods: Sustained-release formulations of Levosulpiride were prepared through direct compression using various cellulose derivatives such as CMC sodium, HPC, and HPMC in different polymer-to-drug weight ratios as release-modifying polymers.

Immunohistochemical determination of estrogen and progesterone receptors in breast cancer: relationship with clinicopathologic factors in 302 patients in Ivory Coast.

Background: Breast cancer is a heterogeneous and a hormone-dependent disease. The detection of the estrogen receptor (ER) and progesterone receptor (PgR) is crucial for prognostic evaluation and treatment choice of breast cancer for clinical practice. The purpose of this study was to evaluate the expression of the hormonal receptors, their distribution, and their correlation with clinicopathologic prognostic parameters for the improvement of the patients' treatment in Ivory Coast.