Endemic High-Risk Clone ST277 Is Related to the Spread of SPM-1-Producing during the COVID-19 Pandemic Period in Northern Brazil.

is a high-priority bacterial agent that causes healthcare-acquired infections (HAIs), which often leads to serious infections and poor prognosis in vulnerable patients. Its increasing resistance to antimicrobials, associated with SPM production, is a case of public health concern. Therefore, this study aims to determine the antimicrobial resistance, virulence, and genotyping features of strains producing SPM-1 in the Northern region of Brazil.

Clonal dissemination of highly virulent strains producing KPC-2 in food-producing animals.

is a Gram-negative bacterium presenting intrinsic resistance to polymyxins that has emerged as an important human pathogen. Although previous studies reported the occurrence of multidrug-resistance (MDR) isolates in the nosocomial settings, herein, we described isolates of this extensively drug-resistant (XDR) species recovered from stool samples of food-producing animals in the Brazilian Amazon region. Three carbapenem-resistant strains were recovered from stool samples of poultry and cattle.

Genomic characterization of BKC-1-producing Klebsiella pneumoniae strain belonging to high-risk clone sequence type 11 isolated from a river in Brazil.

Carbapenem-resistant Klebsiella pneumoniae is a common cause of healthcare-related infections, and it is widespread in hospitals and diverse environments with potentially serious public health implications. Herein, we have reported the isolation and characterization of an environmental Brazilian Klebsiella carbapenemase (BKC-1)-producing K. pneumoniae strain (IEC1205) isolated in 2018 from a river in the Amazon region, Brazil.

The Spread of NDM-1 and NDM-7-Producing Is Driven by Multiclonal Expansion of High-Risk Clones in Healthcare Institutions in the State of Pará, Brazilian Amazon Region.

Carbapenem resistance among isolates is often related to carbapenemase genes, located in genetic transmissible elements, particularly the gene, which variants are spread in several countries. Recently, reports of isolates harboring the gene have increased dramatically along with the dissemination of epidemic high-risk clones (HRCs). In the present study, we report the multiclonal spread of New Delhi metallo-beta-lactamase (NDM)-producing in different healthcare institutions in the state of Pará, Northern Brazil.

PhageWeb - Web Interface for Rapid Identification and Characterization of Prophages in Bacterial Genomes.

This study developed a computational tool with a graphical interface and a web-service that allows the identification of phage regions through homology search and gene clustering. It uses G+C content variation evaluation and tRNA prediction sites as evidence to reinforce the presence of prophages in indeterminate regions. Also, it performs the functional characterization of the prophages regions through data integration of biological databases.

Draft Genome Sequence of Strain PA06 Isolated from a Subauricular Abscess in an Ovine Host.

We report here the draft genome sequence of PA06, isolated from a subauricular abscess in an ovine host. is a worldwide pathogen of small and large ruminants. The genome comprises 2,320,074 bp, with a G+C content of 52.