Surgically induced necrotizing scleritis (SINS): Is it a standalone condition or a variant of necrotizing scleritis?

Purpose: To report the clinical pattern of surgically induced necrotizing scleritis (SINS) in a tertiary eye care center in Southern India.

Methods: Retrospective analysis of all SINS cases visiting the uveitis clinic of a tertiary eye institute between January 2009 and April 2019.

Results: In total, 15 patients with a median age of 65 (IQR: 52-70) years were included in the study.

An Analysis of the clinical and investigative profile of uveitis in the elderly: First case series from India.

Purpose: To evaluate the spectrum of uveitis occurring after 60 years of age in elderly patients who presented to a tertiary care eye center in India.

Methods: Retrospective study of patients who visited a tertiary eye care institute between January 2010 and July 2020.

Result: Eighty-seven patients developed uveitis after 60 years, with only 44.

Exchanging Anion in CuCo-Carbonate Double Hydroxide for Faradaic Supercapacitors: A Case Study.

A systematic synthetic method involving the anion exchange process was designed and developed to fabricate the superior functioning three-dimensional (3-D) urchin-architectured copper cobalt oxide (CuCoO; CCO) and copper cobalt sulfide (CuCoS; CCS) electrode materials from copper-cobalt carbonate double hydroxide [(CuCo)(CO)(OH); CCH]. The effective tuning of chemical, crystalline, and morphological properties was achieved during the derivatization process of CCH, based on the anion exchange effect and phase transformation without altering the 3-D spatial assembly. Benefiting from morphological and structural advantages, CCO and CCS exhibited superior electrochemical activity with capacity values of 1508 and 2502 C g at 10 A g to CCH (1182 C g at 10 A g).

Visual outcome in pediatric uveitis: A retrospective data review in 277 children.

Purpose: This study aimed to describe visual outcomes in cases of pediatric uveitis in an Indian population and to analyze various factors affecting these outcomes.

Methods: Single-center, retrospective chart review of 277 cases of uveitis in patients under the age of 18 years. Variables assessed included age and sex distribution, anatomical location of uveitis, systemic associations, complications, and various treatment strategies used, including long-term immunomodulation and surgical management of complications if required.

Ocular manifestations of HLA B 27 associated uveitis: a study of 255 cases from a tertiary eye care centre from South India.

Purpose: To describe the clinical profile of HLA B-27-associated uveitis in Indian population.

Method: We conducted a retrospective review of medical records of 431 eyes of 255 consecutive patients with HLA B-27-associated uveitis, presented to our institute between 2012 and 2017.

Result: The study observed a male preponderance (75.

Clinical profile of patients with anterior nodular scleritis in India.

Purpose: To report the clinical profile of a series of anterior nodular scleritis in Indian population.

Methods: We conducted a retrospective review of medical records of 140 eyes of 123 consecutive patients with nodular scleritis who presented to a tertiary eye care institute between 2007 and 2018.

Results: The mean age at presentation was 46.

Cataract Surgery in the Setting of Scleritis.

: To report the clinical profile of cataract and its surgical management in a scleritis cohort from India.: We conducted a retrospective review of medical records of 39 eyes of 32 consecutive patients with scleritis who underwent cataract surgery in a tertiary eye care institute.: The mean age at presentation was 50.

Pediatric Sympathetic Ophthalmia: 20 Years of Data From a Tertiary Eye Center in India.

Purpose: To examine the clinical profile of sympathetic ophthalmia among the pediatric age group.

Methods: Retrospective review of patients 18 years and younger with sympathetic ophthalmia seen in a tertiary eye care center between 1997 and 2017.

Results: Of 20 patients included in the study, 70% were male.

The Collaborative Ocular Tuberculosis Study (COTS) Consensus (CON) Group Meeting Proceedings.

An international, expert led consensus initiative was set up by the Collaborative Ocular Tuberculosis Study (COTS) group to develop systematic, evidence, and experience-based recommendations for the treatment of ocular TB using a modified Delphi technique process. In the first round of Delphi, the group identified clinical scenarios pertinent to ocular TB based on five clinical phenotypes (anterior uveitis, intermediate uveitis, choroiditis, retinal vasculitis, and panuveitis). Using an interactive online questionnaires, guided by background knowledge from published literature, 486 consensus statements for initiating ATT were generated and deliberated amongst 81 global uveitis experts.

Inverted Flap Technique for Large Macular Hole Secondary to Chronic Uveitis.

Macular hole is a defect in the neurosensory retina at the center of the fovea, seen in 8.3% of the postuveitic cases. In such cases, macular holes tend to be large and are associated with structural damage in the outer retinal layers.

Phacotrabeculectomy in Eyes With Uveitic Glaucoma: A Retrospective Case-Control Study.

Precis: Phacotrabeculectomy with adjunctive mitomycin C is a good option for the management of coexisting cataract and glaucoma. Strict preoperative control of inflammation and close follow-up are essential in the management of eyes with uveitic glaucoma (UG).

Purpose: The purpose of this study was to compare the outcomes of phacotrabeculectomy with adjunctive antimetabolites in the management of patients with UG and patients with primary open-angle glaucoma (POAG).

Antineutrophil cytoplasmic antibody-positive scleritis: Clinical profile of patients from a tuberculosis-endemic region.

Purpose: To report the clinical profile of a series of antineutrophil cytoplasmic antibody (ANCA)-associated scleritis in Indian population.

Methods:: We conducted a retrospective review of medical records of 33 eyes of 26 consecutive patients with scleritis, who tested positive for either antibody to proteinase 3 [anti-PR3/cytoplasmic antineutrophil cytoplasmic antibody (cANCA)] or myeloperoxidase [anti-MPO/perinuclear anti-neutrophil cytoplasmic antibody (pANCA)] between 2006 and 2015.

Results:: The mean age at presentation was 54.

Scleroderma-related choroiditis.

A 34-year-old female a known scleroderma patient presented to us with ocular manifestations in the form choroiditis along with optic nerve involvement. Blood investigations were done, and the ocular findings were confirmed by fundus fluorescein angiography. She was successfully managed with systemic steroid therapy.

Clinical Profile of Scleritis in Children.

: To describe the clinical pattern of scleritis in patients ≤16 years of age at a tertiary care eye hospital in India. : The medical records of 24 eyes of 20 children with scleritis were included in this retrospective study. Collected data included age, subsets of uveitis, best corrected visual acuities (BCVA), detailed laboratory investigations and treatment.

Postsurgical sympathetic ophthalmia: retrospective analysis of a rare entity.

Purpose: To describe clinical manifestations, management and visual outcome in postsurgical sympathetic ophthalmia (SO).

Methods: Retrospective study.

Results: Mean age of the patients was 41.

Culture and Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) Proven Mycobacterium Tuberculosis Endophthalmitis: A Case Series.

Purpose: To report early confirmation of Mycobacterium tuberculosis (MTB) endophthalmitis by detection of 85B mRNA in vitreous by a reverse transcriptase polymerase chain reaction (RT-PCR) technique.

Methods: Retrospective, interventional case series of 5 patients with MTB endogenous endophthalmitis. Vitreous aspirate was subjected to Ziehl-Neelsen (ZN) staining, BACTEC MicroMGIT culture, RT-PCR targeting the 85B gene, real-time PCR targeting the IS6110 region, and nested PCR targeting the MPB64 gene and IS6110 region.

Incidence and Management of Glaucoma in Vogt Koyanagi Harada Disease.

Purpose: To analyse the prevalence, incidence, and risk factors of glaucoma in Vogt Koyanagi Harada (VKH) disease and study the changes in visual acuity and intraocular pressure (IOP) with treatment.

Materials And Methods: Retrospective chart analysis of 448 eyes of 224 patients of Indian origin diagnosed with VKH disease from January 1990 to December 2013, who had a minimum follow-up of 3 months was performed.

Results: Seventy-one eyes (15.

Paediatric choroidal neovascular membrane secondary to toxoplasmosis treated successfully with anti-vascular endothelial growth factor.

The purpose of this report was to evaluate the role anti-VEGF in management of CNVM secondary to ocular toxoplasmosis. Young female diagnosed as a case of bilateral ocular toxoplasmosis presented with complaints of diminution of vision in the right eye. Fundus examination showed an active CNVM adjacent to toxoplasmosis scar.

Ocular lesions in 1,000 consecutive HIV-positive patients in India: a long-term study.

Background: Ocular lesions in patients on highly active antiretroviral therapy (HAART) have shown changes in disease prevalence and pattern. Although they have been described in the Western population, there are not many such studies in the HAART era from India. This study aims to present the clinical profile, systemic correlation, and visual outcome in HIV-positive patients in relation to HAART in comparison with pre-HAART Indian studies and current Western data.

Tubercular sclerouveitis masquerading as an ocular tumor: a case report.

Purpose: To report the diagnosis of a case of tubercular sclerouveitis, which masqueraded as an ocular tumor.

Design: Case report.

Methods: Retrospective medical chart review including serological, radiological, and histopathological investigative results.