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Publications by authors named "Amal Mathai"

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Synopsis of recent research by authors named "Amal Mathai"

  • - Amal Mathai's research focuses on enhancing the accessibility of structured RNAs for DNA-cleaving enzymes, particularly the 10-23 DNAzyme, to improve RNA detection and manipulation techniques.
  • - In a recent study, Mathai developed a strategy that allows the 10-23 DNAzyme to effectively target purine-pyrimidine junctions in large, structured RNA molecules, overcoming the limitations of traditional cleavage methods.
  • - Another study showcases the integration of DNAzyme-mediated RNA cleavage with rolling circle amplification (RCA) for detecting SARS-CoV-2 genomic RNA, identifying multiple effective DNAzyme variants that exhibit significant cleavage activity.

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