Publications by authors named "Amal M Mahfoz"

Background: Social media in our networks have been exploited as dynamic learning tools and free platforms.

Aims: The main objective of this study is to determine the impact of VARK learning styles (visual (V), aural (A), read/write (R), and kinesthetic (K)) in enhancing parasitological laboratory skills using social media and various learning theories.

Methods: A research sample of 100 chemists working in Mega Alfa labs underwent online learning of laboratory parasitology skills via Facebook posts and WhatsApp dictated messages for an average of 7 weeks.

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  • Zinc Oxide nanoparticles (ZnO NPs) are commonly used in sunscreens for UV protection but raise concerns about toxicity; silica is used to encapsulate them to mitigate this risk.
  • A Vitamin C derivative called Magnesium Ascorpyl Phosphate (MAP) is a strong antioxidant that helps protect skin from UV damage and oxidative stress; combining it with silica-coated ZnO NPs may enhance protection.
  • Research showed that the combination of silica-coated ZnO NPs and MAP nanovesicles effectively protects against UV damage in mice and significantly improves skin condition in human studies by reducing melanin, roughness, and wrinkle depth.
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Inhibition of α-glucosidase and -amylase are key tactics for managing blood glucose levels. Currently, stronger, and more accessible inhibitors are needed to treat diabetes. Indeno[1,2-] quinoxalines-carrying thiazole hybrids were created and described using NMR.

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Background: Trichinella spiralis can affect the brain by inducing inflammatory and vascular changes. Drug management with the antiparasitic drug albendazole can be enhanced by natural compounds such as curcumin. The potential benefit of curcumin as an adjuvant to albendazole in the management of cerebral affection during experimental T.

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Background: Diabetic hepatopathy is a serious complication of poorly controlled diabetes mellitus. An efficient antidiabetic drug which keeps normal liver tissues is not available. The renin-angiotensin system has been reported to be involved in both diabetic state and liver function.

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Background: Asthma is a chronic inflammatory disease characterized by reversible airway obstruction, hyperresponsiveness, and remodeling. Asthma prevalence has increased significantly globally over the last decade, and it remains incurable to this date.

Aims And Objectives: The present study evaluated some of the antiasthmatic medicinal plants to assess their mode of action.

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larvae have very special characters that make them able to completely transform the function of the affected muscle cells towards a self-serving environment, offering them nourishment and protection via what is known as "nurse cells". This setting may be affected by drugs that are used for the treatment of co-morbidities and co-infections as calcium channel blockers, which are widely used in clinical practice. In the present study, the effects of verapamil, ivermectin (IVM), and their combined administration on the parasitic burden, immuno-pathology and angiogenesis were investigated during experimental trichinellosis.

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Background: Oxidative stress is considered the main event in the pathogenesis. of diabetic nephropathy (DN). Zamzam water, being natural alkaline with exceptional characteristics, is capable of enhancing antioxidant mechanisms.

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Epilepsy is considered a major serious chronic neurological disorder, characterized by recurrent seizures. It is usually associated with a history of a lesion in the nervous system. Irregular activation of inflammatory molecules in the injured tissue is an important factor in the development of epilepsy.

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Sensory contact model (SCM) permits the evolution of diverse psychopathological states by the repeated antagonistic interactions between male mice. Biphenyl dimethyl dicarboxylate (DDB) is used as a hepatoprotective agent. The present work aimed to study the possible effects of DDB on social behavior developed by SCM by studying its effects on the transformation process to aggressive and submissive behaviors.

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Article Synopsis
  • Status epilepticus (SE) is a serious form of epilepsy with a high risk of mortality, highlighting the need for more effective and safer treatment options.
  • Recent research indicates that dietary therapies like the ketogenic diet and the use of vitamin D (vit-D) may have neuroprotective benefits for managing seizures.
  • A study in rats found that vit-D alone or combined with lamotrigine improved cognitive function and reduced brain oxidative stress, suggesting its potential as a supportive treatment for epilepsy, though further clinical trials are necessary.
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Since chronic kidney disease due to diabetic nephropathy (DN) is becoming an ever larger health burden worldwide, more effective therapies are desperately needed. In the present study, the anti-diabetic and renoprotective effects of aliskiren have been evaluated in streptozotocin (STZ)-induced DN in rats. DN was induced by a single intraperitoneal injection of STZ (65 mg/kg).

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Evidence shows that inflammatory and immune processes within the brain might account for the pathophysiology of epilepsy. Therefore, developing new antiepileptic drugs that can modulate seizures through mechanisms other than traditional drugs is required for the treatment of refractory epilepsy. This study aims to determine the relationship between brain inflammation and epilepsy, to examine the contribution of some biochemical parameters involved in brain inflammation, and to address the effect of pharmacological interventions using some anti-inflammatory and immunomodulatory drugs in an experimental epilepsy model.

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