Ecological multivariate assisted spectrophotometric methods for determination of antipyrine and benzocaine HCl in presence of antipyrine official impurity and benzocaine HCl degradant: toward greenness and whiteness.

A simple and green chemometrics-assisted spectrophotometric technique has beendeveloped and validated for the determination of antipyrine (ANT) and benzocaine HCl (BEN) along with the official impurity of ANT, antipyrine impurity A (ANT imp-A), and the degradation product of BEN, p-amino benzoic acid (PABA), in their quaternary mixture. Three models were developed and compared: partial least squares (PLS), artificial neural networks (ANN), and multivariate curve resolution-alternating least squares (MCR-ALS) where the four studied drugs were successfully quantified. The quantitative determination of the studied drugs was assessed using percentage recoveries, standard errors of prediction, and root mean square errors of prediction.

Bayesian and non-bayesian analysis for stress-strength model based on progressively first failure censoring with applications.

This article examines the estimate of ϑ = P [T < Q], using both Bayesian and non-Bayesian methods, utilizing progressively first-failure censored data. Assume that the stress (T) and strength (Q) are independent random variables that follow the Burr III distribution and the Burr XII distribution, respectively, with a common first-shape parameter. The Bayes estimator and maximum likelihood estimator of ϑ are obtained.

[Guidelines for the prevention, diagnosis and treatment of obesity. Update 2024].

This document updates the "Clinical practice guidelines for the prevention, diagnosis and treatment of obesity" issued by the Nutrition Committee of the Argentine Pediatric Society, published in Archivos Argentinos de Pediatría in 2011. Obesity has a multifactorial etiology. It is recommended to diagnose it taking into account anthropometry, personal and family history, and clinical data that indicate complications (sleep apnea, elevated alanine transaminase and/or glycemia, and other components of the metabolic syndrome).

Statistical inference and data analysis for inverted Kumaraswamy distribution based on maximum ranked set sampling with unequal samples.

A very useful modification to ranked set sampling (RSS) that allows a larger set size without significantly increasing ranking errors is the maximum ranked set sampling with unequal samples (MRSSU) approach. This article covers the parameter estimation of the inverted Kumaraswamy distribution using MRSSU and RSS designs. The maximum likelihood and Bayesian estimation techniques are considered.

Different estimation techniques and data analysis for constant-partially accelerated life tests for power half-logistic distribution.

Partial accelerated life tests (PALTs) are employed when the results of accelerated life testing cannot be extended to usage circumstances. This work discusses the challenge of different estimating strategies in constant PALT with complete data. The lifetime distribution of the test item is assumed to follow the power half-logistic distribution.

Estimation methods based on ranked set sampling for the power logarithmic distribution.

The sample strategy employed in statistical parameter estimation issues has a major impact on the accuracy of the parameter estimates. Ranked set sampling (RSS) is a highly helpful technique for gathering data when it is difficult or impossible to quantify the units in a population. A bounded power logarithmic distribution (PLD) has been proposed recently, and it may be used to describe many real-world bounded data sets.

Precision enhancement in variance estimation for complex environmental populations using adaptive cluster sampling.

Estimating dispersion in populations that are extremely rare, hidden, geographically clustered, and hard to access is a well-known challenge. Conventional sampling approaches tend to overestimate the variance, even though it should be genuinely reduced. In this environment, adaptive cluster sampling is considered to be the most efficient sampling technique as it provides generally a lower variance than the other conventional probability sampling designs for the assessment of rare and geographically gathered population parameters like mean, total, variance, etc.

Effect of thyme, ginger, and their nano-particles on growth performance, carcass characteristics, meat quality and intestinal bacteriology of broiler chickens.

This study was conducted to evaluate the effects of thyme, ginger, and their nano-particles, as alternatives to antibiotic growth promotors (AGP), on productive performance, carcass traits, meat quality and gut health of broiler chickens. A total of 270 one-day-old broiler chicks were randomly distributed into 6 groups, each consisting of 3 replicates (n = 15 chicks/replicate). The birds in group 1 were fed the control diet which contained neither antibiotic growth promotors nor phytogenic feed additives (PFA).

Application of gelatin-based zinc oxide nanoparticles bionanocomposite coatings to control Listeria monocytogenes in Talaga cheese and camel meat during refrigerated storage.

Listeria monocytogenes is a concerning foodborne pathogen incriminated in soft cheese and meat-related outbreaks, highlighting the significance of applying alternative techniques to control its growth in food. In the current study, eco-friendly zinc oxide nanoparticles (ZnO-NPs) were synthesized using Rosmarinus officinalis, Punica granatum, and Origanum marjoram extracts individually. The antimicrobial efficacy of the prepared ZnO-NPs against L.

The Role of Musculoskeletal Training During Return to Performance Following Relative Energy Deficiency in Sport.

Background: Relative energy deficiency in sport (REDs) is a condition that is associated with negative health and performance outcomes in athletes. Insufficient energy intake relative to exercise energy expenditure, resulting in low energy availability, is the underlying cause, which triggers numerous adverse physiological consequences including several associated with musculoskeletal (MSK) health and neuromuscular performance.

Purpose: This commentary aims to (1) discuss the health and performance implications of REDs on the skeletal and neuromuscular systems and (2) examine the role that MSK training (ie, strength and plyometric training) during treatment and return to performance following REDs might have on health and performance in athletes, with practical guidelines provided.

Rapid and sensitive in situ detection of heavy metals in fish using enhanced Raman spectroscopy.

Heavy metals have been widely applied in industry, agriculture, and other fields because of their outstanding physics and chemistry properties. They are non-degradable even at low concentrations, causing irreversible harm to the human and other organisms. Therefore, it is of great significance to develop high accuracy and sensitivity as well as stable techniques for their detection.

A probe of new molecularly imprinted solid-phase extraction coupled with HPLC-DAD and atomic absorption spectrophotometry for quantification of tetracycline HCl, metronidazole and bismuth subcitrate in combination with their official impurities: Application in dosage form and human plasma.

The integration of molecular imprinting technique with chromatographic one has a great impact on the assay's selectivity and sensitivity. Herein, a molecularly imprinted solid-phase extraction associated with high performance liquid chromatography (MISPE-HPLC) was employed for simultaneous determination of the co-formulated drugs; tetracycline hydrochloride (TET) and metronidazole (MET), in plasma and in their anti-H-pylori drug for the first time. Two sorts of molecularly imprinted polymers (MIPs) were fabricated using TET and MET as the template molecules, while ethylene glycol dimethacrylate and methacrylic acid were used as a cross-linker and a monomer, respectively.

A novel weighted family of probability distributions with applications to world natural gas, oil, and gold reserves.

Recent innovations have focused on the creation of new families that extend well-known distributions while providing a huge amount of practical flexibility for data modeling. Weighted distributions offer an effective approach for addressing model building and data interpretation problems. The main objective of this work is to provide a novel family based on a weighted generator called the length-biased truncated Lomax-generated (LBTLo-G) family.

Application of multivariate chemometrics tools for spectrophotometric determination of naphazoline HCl, pheniramine maleate and three official impurities in their eye drops.

This work is concerned with exploiting the power of chemometrics in the assay and purity determination of naphazoline HCl (NZ) and pheniramine maleate (PN) in their combined eye drops. Partial least squares (PLS) and artificial neural network (ANN) were the chosen models for that purpose where three selected official impurities, namely; NZ impurity B and PN impurities A and B, were successfully determined. The quantitative determinations of studied components were assessed by percentage recoveries, standard errors of prediction as well as root mean square errors of prediction.

Molecular imprinted polymer-based potentiometric approach for the assay of the co-formulated tetracycline HCl, metronidazole and bismuth subcitrate in capsules and spiked human plasma.

Background: An anti-H-pylori co-formulated mixture of tetracycline HCl (TET), metronidazole (MET), and bismuth subcitrate (BSC) is recently available. Only two chromatographic and spectrophotometric methods are reported for determining those drugs simultaneously where the effect of impurities that could be present as well as the biological fluids matrix influence do not be taken into consideration. There is a need to develop an easy-to-use potentiometric technique for analysis of TET, MET, and BSC in their co-formulated capsules, in presence of some official impurities and in spiked human plasma.

Degradation and energy performance evaluation of mono-crystalline photovoltaic modules in Egypt.

Degradation reduces the capability of solar photovoltaic (PV) production over time. Studies on PV module degradation are typically based on time-consuming and labor-intensive accelerated or field experiments. Understanding the modes and methodologies of degradation is critical to certifying PV module lifetimes of 25 years.

Inference and quantile regression for the unit-exponentiated Lomax distribution.

In probability theory and statistics, it is customary to employ unit distributions to explain practical variables having values between zero and one. This study suggests a brand-new distribution for modelling data on the unit interval called the unit-exponentiated Lomax (UEL) distribution. The statistical aspects of the UEL distribution are shown.

Assessment of Knowledge and Perception of Sodium-Glucose Co-transporter 2 (SGLT-2) Inhibitors Prescription among Physicians in Saudi Arabia.

Background: Sodium-glucose cotransporter 2 inhibitors are a new class of medications that have been proven to improve both glycemic control and cardio-renal outcomes. The knowledge, attitude, and perception toward their prescriptions in Jazan, Saudi Arabia, are still unknown.

Objective: The study aimed to measure the level of knowledge and attitude toward sodium-glucose cotransporter 2 inhibitors prescription among physicians in the Jazan region, Saudi Arabia.

Molecular Identification, Pathogenesis, and Life Cycle of from Cattle () in New Valley Governorate, Egypt.

was identified by molecular methods from an intermediate host, cattle (), in El-Kharga, New Valley Governorate, Egypt, and its life cycle and pathogenicity were studied in the final host, dogs (). 600 slaughtered cattle aged 6-8 years (480/120 males/females) were included. In addition, three laboratory-bred, coccidian-free puppies aged 2-3 months were fed infected bovine muscles to locate the definitive host and analyze sporogony.

Acceptance sampling plans for the three-parameter inverted Topp-Leone model.

The quadratic rank transmutation map is used in this article to suggest a novel extension of the power inverted Topp-Leone distribution. The newly generated distribution is known as the transmuted power inverted Topp-Leone (TPITL) distribution. The power inverted Topp-Leone and the inverted Topp-Leone are included in the recommended distribution as specific models.