Diagnostic performance of rapid antigen test for COVID-19 and the effect of viral load, sampling time, subject's clinical and laboratory parameters on test accuracy.

Background: Egypt was among the first 10 countries in Africa that experienced COVID-19 cases. The sudden surge in the number of cases is overwhelming the capacity of the national healthcare system, particularly in developing countries. Central to the containment of the ongoing pandemic is the availability of rapid and accurate diagnostic tests that could pinpoint patients at early disease stages.

Sublingual Versus Subcutaneous Immunotherapy as regards Efficacy and Safety in Respiratory Allergic Patients.

Subcutaneous immunotherapy (SCIT) is a well-established treatment modality for allergic patients that has been successfully used for many decades. Sublingual immunotherapy (SLIT) was introduced over the last 20 years as a safer alternative to SCIT with no single case of mortality has ever been reported with it. The aim of this study was to evaluate the efficacy and safety of SLIT versus SCIT in treating respiratory allergic patients.

House dust mites among allergic patients at the Allergy and Immunology Unit, Zagazig University: an immunologic and serologic study.

In the twenty-first century, the occurrence of allergic diseases has increased. Prevention and control of house dust mites (HDMs) are required as they play a major role in allergic conditions. The present work aimed to detect HDM allergy ( and ) among allergic patients attending the Allergy and Immunology Unit, Zagazig University.

Serum Thymus and Activation Regulated Chemokine (TARC), IL- 18 and IL-18 Gene Polymorphism as Associative Factors with Atopic Dermatitis.

Atopic dermatitis (AD) is a worldwide chronic inflammation of skin.Many factors and chemokines play role in pathogenesis of AD. Identifying the reliable biomarkers to diagnose and assess severity of AD is important.

Impact of Some Ecological Factors on Fecal Contamination of Drinking Water by Diarrheagenic Antibiotic-Resistant in Zagazig City, Egypt.

Fecal contamination of drinking water is a major health problem which accounts for many cases of diarrhea mainly in infants and foreigners. This contamination is a complex interaction of many parameters. Antibiotic resistance among bacterial isolates complicates the problem.

Serum Anti-TPO and TPO Gene Polymorphism as a Predictive Factor for Hidden Autoimmune Thyroiditis in Patient with Bronchial Asthma and Allergic Rhinitis.

Thyroid peroxidase (TPO) is the key enzyme in the biosynthesis of thyroid hormones T3 and T4. Autoimmune thyroiditis is a common disorder affecting 10% of population worldwide. A key feature of autoimmune thyroiditis is the presence of anti TPO antibodies, and some mutation of the TPO gene.

Seroprevalence of Helicobacter pylori infection among family members of infected and non-infected symptomatic children.

This study determined the prevalence of seropositivity of anti-H. pylori IgG antibodies, and evaluated some socio-epidemiologic characteristics among family members of infected and non-infected symptomatic children. One hundred children with upper gastrointestinal symptoms without previous H.

Hepatitis C Virus NS5B Sequence-Based Genotyping Analysis of Patients From the Sharkia Governorate, Egypt.

Background: Chronic hepatitis C virus infection and its sequela are major health problems facing the Egyptian community. The high prevalence and spread rates of the disease require serious actions to stop or decrease these rates. Determination of HCV genotypes and subgenotypes adds significant knowledge about the epidemiology of the disease, and provides an added value in the decision making process of what strategy to follow and what therapy response to expect.

Differential effects of alprazolam and clonazepam on the immune system and blood vessels of non-stressed and stressed adult male albino rats.

Benzodiazepines belongs to one of the most commonly used anxiolytic and anticonvulsant drugs in the world. Full description of toxic effects on different organs is lacking for nearly all the current benzodiazepines. The aim of the current work was to study the immunologic and vascular changes induced by sub-chronic administration of alprazolam and clonazepam in non-stressed and stressed adult male albino rats.