Publications by authors named "Amal F Sam"

Background: Pretransplant colonization with carbapenem-resistant Enterobacterales (CRE) is associated with poorer post-liver transplantation (LT) outcomes. We aimed to analyze the incidence and risk factors for CRE colonization in adult living-donor LT recipients from January 2019 to September 2022 and its impact on post-LT outcomes.

Methods: Relevant perioperative parameters including bacteremia within one month post LT were recorded.

View Article and Find Full Text PDF

Background: Central venous catheters (CVCs) are the choice of venous access if patients require vasoactive drugs or multiple infusions but are not free of adverse effects. They should be removed when deemed unnecessary. In cases of difficult venous access, long peripheral catheters (LPCs) placed in the bigger veins of the arm under sonographic guidance are a good option.

View Article and Find Full Text PDF

Objectives: Mean systemic filling pressure is a key determinant of venous return and cardiovascular function, with potential implications for hemodynamic stability in surgical interventions, such as liver transplantation. In this prospective observational pilot study, we investigated changes in mean systemic filling pressure in patients undergoing living related donor liver transplant (primary outcome) and its correlation with various hemodynamic and intraoperative parameters (secondary outcomes).

Materials And Methods: This study was conducted at a tertiary care hospital between May 2020 and October 2020.

View Article and Find Full Text PDF

Introduction: Acute kidney injury (AKI) is a prevalent complication of liver transplantation, leading to prolonged hospital or intensive care unit stay and significant morbidity. Recently, biomarkers such as neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C have been investigated for their potential role in the early detection of AKI in liver transplantation patients.

Method: Our study comprised 60 patients with end-stage liver disease undergoing living donor liver transplantation.

View Article and Find Full Text PDF

Severe hemodynamic instability is observed during portal vein de-clamping in the form of post-reperfusion syndrome in liver transplantation. The protective effect of magnesium on inflammation and ischemia-reperfusion injuries of various organs is evident, but its role in the prevention of post-reperfusion syndrome in liver transplantation is not clear. We investigated the effect of magnesium sulphate on the incidence of post-reperfusion syndrome during living donor liver transplantation.

View Article and Find Full Text PDF

Introduction: The effect of sarcopenia, malnutrition, and functional status on immediate post liver transplantation outcome is not well established. Most studies on sarcopenia are related to 1 and 3-year mortality. Studies evaluating the effect of malnutrition are at least a decade old.

View Article and Find Full Text PDF

Ischemic and reperfusion injury (IRI) occurs during organ transplantation. IRI during liver transplantation is well studied and established; results in coagulopathy due to release of heparin-like substances and platelet trapping. During renal transplantation, similar IRI phenomenon occurs, and thromboelastography (TEG) can be used to detect and manage coagulopathy.

View Article and Find Full Text PDF