Publications by authors named "Amal Alkhotani"

Objective: At the beginning of the COVID-19 pandemic, it was recommended to provide emergency dental care and avoid aerosol-generating procedures (AGPs) when possible. This study aimed to determine how Saudi Arabian pediatric patients utilized emergency dental services at the national level at the beginning of the COVID-19 pandemic and what situations required an AGP.

Methods: Data was collected from all Ministry of Health dental facilities in Saudi Arabia between March and May 2020.

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Article Synopsis
  • The study explored breastfeeding initiation and continuation rates among women with epilepsy at a tertiary care center in Makkah from 2019 to June 2023.
  • A total of 48 women were interviewed, revealing that 68.6% practiced breastfeeding, but only 12.1% sustained it for 6 months or more, with many resorting to bottle feeding.
  • Factors influencing breastfeeding included urban living, number of antiseizure medications (ASMs), seizure control during pregnancy, and type of delivery, highlighting a generally low rate of breastfeeding in this population.
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Background: Entrustable professional activities (EPAs) define the core tasks that a graduating rheumatologist needs to perform independently in practice. The objective of this study was to develop and validate EPAs for rheumatology fellowship training programs in Saudi Arabia.

Methods: Experts met to develop an initial set of potential end-of-training EPAs by conducting a comprehensive literature review of EPAs and studying the Saudi rheumatology fellowship curriculum.

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Encephalopathy is a diffuse brain dysfunction that results from systemic disorder. Patients with diffuse encephalopathy are at risk of developing clinical and electrographic seizures. The aim of this study is to assess the prevalence of electrographic seizures in a setting of encephalopathy and the clinical and electroencephalogram predictors.

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Background Headache disorders, particularly migraines, significantly impact public health globally. The Global Burden of Disease (GBD) report highlights migraines as the second leading cause of disability worldwide, especially among women under 50. Hormonal changes, particularly estrogen, play a role in primary headaches like migraines, and this connection becomes important during pregnancy due to physiological changes.

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Background: One of the most prevalent pediatric medical conditions is attention-deficit/hyperactivity disorder (ADHD). It is characterized by symptoms of hyperactivity, impulsivity, and/or inattention. The first people to notice a child's ADHD symptoms are typically their teachers, who may then offer data that are typically helpful in its diagnosis.

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Article Synopsis
  • The Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) has been adapted for adolescents, filling a gap as no previous version existed for this age group.
  • A Delphi process involving experts led to modifications that make the assessment tools developmentally appropriate for individuals aged 10-19, focusing on physical and psychosocial health.
  • The adapted DC/TMD includes revised questionnaires and additional assessments for anxiety, depression, stress, and sleep disorders, aiming for reliability and validity in clinical and research settings globally.
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Background: Ictal semiology is important to aid the diagnosis of seizure type. Patients frequently require admission to an epilepsy monitoring unit (EMU) to reach a correct diagnosis of epilepsy type. Some patients may exhibit unusual ictal phenomena that can lead to the diagnosis of psychogenic seizures.

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Article Synopsis
  • - The study presents adaptations of the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) specifically designed for children aged 6-9, filling a gap since no previous adaptations existed.
  • - Through expert consultation, developmental changes were made to both Axis I and Axis II, including adjustments in language for questionnaires, incorporation of general health assessments, and new protocols for assessing psychosocial factors like anxiety and sleep disorders.
  • - The newly adapted criteria are suitable for clinical and research use, requiring further reliability and validity testing, and will undergo translation for global application in various languages.
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Background:  ​​Epilepsy is one of the most common neurological disorders in the pediatric age group, and teachers have a crucial role in providing appropriate epilepsy first aid. This study aims to assess the knowledge of and attitude toward epilepsy and seizure first aid among male teachers in the Mecca region, Saudi Arabia.

Methods:  This cross-sectional study used an online self-administered questionnaire.

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Introduction Stroke has become one of the most severe causes of long-term neurological impairment and disability and is considered one of the leading causes of mortality worldwide. This study aimed to determine time delays in stroke patients from symptoms onset to treatment with tissue plasminogen activator (tPA) initiation in King Abdullah Medical City Specialist Hospital, Makkah, Saudi Arabia. Patients and methods We reviewed 81 patients who suffered from acute stroke.

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Despite the recent advancements in the treatment of acute ischemic stroke, the delayed patient arrival to emergency department or hospital serve as crucial factor for the selection of appropriate intervention program. This study was aimed to identify factors associated with late hospital arrival for patients with acute ischemic stroke in Makkah, Saudi Arabia. A prospective cross-sectional study was carried out at Al-Noor Specialist Hospital among 98 enrolled patients with the mean age of 60.

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Background: Epilepsy is a neurological disorder characterized by a persistent propensity to generate recurring epileptic seizures. Young adults such as university students can bridge the gap and improve attitudes toward patients with epilepsy and reduce stigma. This study aims to assess the knowledge and attitude of university students in the city of Makkah about epilepsy.

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Introduction Multiple sclerosis (MS) is an autoimmune disease that can be disabling to patients. Smoking has been proposed to be a risk factor for MS and to increase the risk of progression of the disease and its severity. However, it is still not clear how smoking affects people with MS (PwMS) regarding disease phenotype, symptoms, relapses, course, and disability.

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In young children, epilepsy, a disorder marked by recurring seizures, is frequent. Schoolteachers play an important role in the development of young children and hence have a big impact on their psychosocial development. This study was carried out to examine the available data from Saudi Arabia in order to better understand the knowledge gap among Saudi instructors.

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Several studies have reported an association between temporomandibular disorder pain (TMD-P) and emotional disorders in children and adolescents. However, no studies have reported if self-reported TMD-P in Saudi Arabia is associated with psychosocial symptoms. Therefore, the current study aimed to evaluate the association between self-reported TMD-P with depression, anxiety and somatic problems in children and adolescents in Saudi Arabia.

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Objectives: To assess awareness of the neurological manifestation of COVID-19 on the Saudi population.

Methods: This was a cross-sectional study conducted using a Google Form survey to obtain responses randomly from the Saudi population between February and March 2021 using social media.

Results: A total of 831 participants completed the questionnaire.

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Introduction: Epilepsy is a common neurological disease. Patients with epilepsy are at risk of developing seizure at any time. The aim of this study was to assess the effects of health education on schoolteachers' first aid management of epileptic seizure.

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Introduction Multiple sclerosis (MS) is a chronic disease of progressive demyelination in the central nervous system and carries a significant risk for depression and other psychological difficulties associated with low quality of life. There is a paucity of data on the prevalence of anxiety and depression in Saudi Arabia among patients with MS. We conducted a cross-sectional study to determine the prevalence of anxiety and depression in Saudi Arabia among patients with MS by age, disease severity, compliance to medication, and social support.

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Article Synopsis
  • There is currently no standardized psychosocial assessment for children and adolescents with temporomandibular disorders (TMD), unlike the established criteria for adults.
  • The study aims to develop a new assessment tool for young patients by adapting existing adult frameworks and incorporating additional measures for psychosocial health.
  • Using a modified Delphi method, experts reached a consensus on the assessment tools needed, resulting in a comprehensive evaluation framework that includes pain-related disability, depression, anxiety, and other psychological factors for children and adolescents with TMD.
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Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract that is frequently accompanied by systemic complications including peripheral neuropathies. Anti-tumor necrosis factor-alpha agents such as infliximab are an established treatment for immune-mediated diseases. However, they have been associated with adverse effects, including local reactions, infections, congestive heart failure, malignancies, and, rarely, they can cause neurological adverse effects on the central nervous system, as well as peripheral nervous system demyelination.

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Article Synopsis
  • The study highlights the need for a standardized approach to diagnosing temporomandibular disorders (TMD) in children and adolescents, as current methods rely heavily on self-reports and proxy reports.* -
  • Using a modified Delphi method, experts from around the world developed and adapted diagnostic criteria specifically for evaluating TMD in younger populations through discussions and surveys.* -
  • Ultimately, the study resulted in two new adapted protocols for diagnosing TMD in children and adolescents, achieving expert consensus on the updated criteria.*
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Objectives: To assess and quantify the impact COVID-19 has had thus far on ischemic stroke admission rate and severity (National Institutes of Health Stroke Scale (NIHSS) score) at a single tertiary center in Makkah, Saudi Arabia.

Methods: This is a retrospective analysis performed on admitted cases with definitive final diagnoses of transient ischemic attack (TIA) and ischemic stroke at King Abdullah Medical City in Makkah between January 1, 2020 and July 2020.

Results: Sixty-nine patients were included in our study, 41 of whom presented at our facility before the pandemic and 29 during the pandemic.

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Atrial fibrillation is the most common cardiac arrhythmia. Anticoagulation therapy effectively reduces systemic embolization in patients with non-valvular atrial fibrillation, but intracranial hemorrhage (ICH) is a major possible complication. This study assessed the real-time rate of rivaroxaban-associated ICH in Saudi patients.

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