Characterizing camel milk constituents in the Sprague-Dawley rats' blood: A comparative profile with cow's milk attributes.

A comparative study of the hypoglycemic and hypotriglyceridemic effects of raw and pasteurized camel milk was conducted on the lipid profiles of six groups of male normal and diabetic Sprague-Dawley rats (age, 7-8 weeks, 5/group). The standard procedure to induce diabetes in rats was to administer a single intraperitoneal injection of streptozotocin (55 mg/kg, body weight). Rats with fasting blood glucose levels higher than 250 mg/dL were considered diabetics.

Validating the preeminence of biochemical properties of camel over cow and goat milk during the Covid-19.

In the light of the Covid-19 pandemic outbreak, and the need-of-the-hour to boost immunity to residents, especially those residing in an arid environment, a comparative study was made on the physical and biochemical properties of dairy milk. This novel study in Kuwait revealed the lesser consumed pseudoruminant camel milk as a better potential source of dietary inclusion and an immune booster over true ruminants-cow's and goat's milk. Analysis using a wide array of instruments determining the physical characteristics in camel's milk (pH, conductivity, specific gravity, moisture, and total solids), biochemical constituents (crude protein (CP), nonprotein (NP), and fat), and inorganic constituents (K-919; Ca-907; Zn-4.

c-myc antisense oligonucleotides sensitize human colorectal cancer cells to chemotherapeutic drugs.

Background/aims: Overexpression of the c-myc oncogene frequently occurs in both colon tumors and colon carcinoma cell lines. We examined the sensitization of human colorectal cancer cells to chemotherapeutic drugs using c-myc antisense (AS) phosphorothioate oligonucleotides ([S]ODNs).

Methods: Cancer cells were treated with c-myc [S]ODNs, taxol, 5-fluorouracil (5-FU), doxorubicin and vinblastine individually and in combination.

Antisense oligodeoxynucleotide directed against c-myb has anticancer activity and potentiates the antiproliferative effect of conventional anticancer drugs acting by different mechanisms in human colorectal cancer cells.

The C-MYB proto-oncogene encodes a DNA-binding protein with transactivation properties that plays an important regulatory role in cell proliferation and differentiation. Overexpression of C-MYB in colonic tumors compared to normal mucosa suggests that c-myb may play a role in the malignant transformation of colonic mucosa and that inhibition of c-myb expression may suppress, to some extent, the proliferation of neoplastic cells. Complete suppression of tumor cell proliferation may require inhibition of multiple growth-promoting genes.