Graft-artery junctions: design optimization and CAD development.

Designing and manufacturing of vascular prosthesis for arterial bypass grafts is a very complex problem. The process involves the selection of suitable geometry, materials of appropriate characteristics, and manufacturing technique capable of constructing prosthesis in a cost-effective manner. In this chapter, all engineering aspects related to the design and optimization of an artificial graft are presented and discussed.

Numerical analysis of coronary artery bypass grafts: an over view.

Arterial bypass grafts tend to fail after some years due to the development of intimal thickening (restenosis). Non-uniform hemodynamics following a bypass operation contributes to restenosis and bypass failure can occur due to the focal development of anastomotic intimal hyperplasia. Additionally, surgical injury aggravated by compliance mismatch between the graft and artery has been suggested as an initiating factor for progress of wall thickening along the suture line Vascular grafts that are small in diameter tend to occlude rapidly.