Oligo-Metastatic Ductal Breast Carcinoma Presenting as a Subcutaneous Nape Nodule: A Case Report.

Breast cancer (BC) in females is the most diagnosed cancer and the leading cause of cancer death in women worldwide, followed by lung, colorectal, and cervical cancers. For oligo-metastatic (OM) cancers, the best definition is a maximum of five metastatic foci, not necessarily located in the same organ or anatomic region, all potentially treatable by ablative local treatment: either surgical resection or radiation when accessible. Oligo-metastatic breast cancer (OM-BC) is currently arising as an emerging entity with more focused research needed to upgrade the guidelines for best management.

Seasonal differences in physical activity, sedentary behaviour, and sleep patterns in people with type 1 diabetes in Kuwait.

Aims: The main aim of the current study was to measure physical activity, sedentary behaviors and sleep levels across the different seasons in people with type 1 diabetes in Kuwait.

Methods: A prospective cross-sectional study was conducted from August 2021 to September 2022. Physical activity and sleep metrics were measured over a 7-day period with a wrist-worn accelerometer (GENEActiv).

Amphetamine-Related Fatalities and Altered Brain Chemicals: A Preliminary Investigation Using the Comparative Toxicogenomic Database.

Amphetamine is a psychostimulant drug with a high risk of toxicity and death when misused. Abuse of amphetamines is associated with an altered organic profile, which includes omega fatty acids. Low omega fatty acid levels are linked to mental disorders.

Assessment of knowledge, accessibility, and adherence to the use of personal protective equipment and standard preventive practices among healthcare workers during the COVID-19 pandemic.

Background: Healthcare workers are at risk of acquiring infectious agents while providing services to patients. Thus, the need for evaluating and closely monitoring healthcare worker knowledge, perception, and adherence levels is critical. This study evaluates the knowledge, accessibility, and adherence regarding personal protective equipment (PPE) and preventive protocols among healthcare workers during the COVID-19 pandemic.

Knowledge, Attitudes, and Practices of High-Risk Patients towards Prevention and Early Detection of Chronic Kidney Disease (CKD) in Saudi Arabia.

Context: Chronic kidney disease (CKD) is characterized by the presence of kidney damage or decreased kidney function. In the Kingdom of Saudi Arabia, the prevalence of CKD is at 5.7%, which represents a high burden on health care systems.

Postnatal exercises: perceived barriers and self-efficacy among women at maternal and children hospital at Najran, kingdom of Saudi Arabia.

Sedentary lifestyle is very high in the Saudi population in general and significantly high among females. Furthermore, some postpartum tradition imposes limited activities during postpartum periods. For women to be active during the postpartum period, they should have enough self-efficacy (SE) to overcome perceived barriers (BP).

Multi-Compartment 3D-Cultured Organ-on-a-Chip: Towards a Biomimetic Lymph Node for Drug Development.

The interaction of immune cells with drugs and/or with other cell types should be mechanistically investigated in order to reduce attrition of new drug development. However, they are currently only limited technologies that address this need. In our work, we developed initial but significant building blocks that enable such immune-drug studies.