Publications by authors named "Amaia Martinez Leon"

Cardiogenic shock (CS) is a complex multifactorial clinical syndrome of end-organ hypoperfusion that could be associated with multisystem organ failure, presenting a diverse range of causes and symptoms. Despite improving survival in recent years due to new advancements, CS still carries a high risk of severe morbidity and mortality. Recent research has focused on improving early detection and understanding of CS through standardized team approaches, detailed hemodynamic assessment, and selective use of temporary mechanical circulatory support devices, leading to better patient outcomes.

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The growing geriatric population presenting with coronary artery disease poses a primary challenge for healthcare services. This is a highly heterogeneous population, often underrepresented in studies and clinical trials, with distinctive characteristics that render them particularly vulnerable to standard management/approaches. In this review, we aim to summarize the available evidence on the treatment of acute coronary syndrome in the elderly.

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Article Synopsis
  • - A new microRNA, hsa-miR-Chr8:96, was discovered as a potential diagnostic marker for acute myocarditis, showing promise in differentiating it from other heart conditions like myocardial infarction.
  • - The research involved analyzing specific immune cells in mice and then validating the findings in human patients, revealing that this microRNA is present in those with myocarditis but not in those with myocardial infarction.
  • - This microRNA demonstrated a high diagnostic accuracy with an area under the curve of 0.927, making it a valuable tool for diagnosing acute myocarditis and potentially reducing reliance on invasive procedures.
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