Effects of ACE inhibition and beta-blockade on female genital structures in spontaneously hypertensive rats.

Introduction And Aim: This study evaluated the possible differences between an angiotensin converting enzyme (ACE) inhibitor and a beta-blocker concerning their potential protective role on female external genitalia in spontaneously hypertensive rats (SHR).

Main Outcome Measures: Morphological changes in the clitoris after antihypertensive treatments.

Methods: For 6 months, SHR received no treatment; SHR + ramipril (RAM), SHR + atenolol (AT), and control Wistar Kyoto (WKY) rats received no treatment.