Publications by authors named "Amadeusz Odroniec"

Article Synopsis
  • Salivary gland tumors can present in various forms, and the WHO has categorized 22 malignant and 11 benign types, with diagnosis relying on imaging and biopsy techniques.
  • A pilot study is exploring the use of peptide biomarkers in saliva to help diagnose these tumors, comparing samples from tumor tissues and healthy individuals.
  • The research identified 109 peptides unique to tumor tissues and patients' saliva, but the lack of consistent peptides across samples suggests tumor variety and may indicate that tumors inhibit the production of specific salivary proteins.
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Context: The hypothalamic-pituitary-gonadal axis's transient activity in infancy, i.e, minipuberty, is considered crucial for male reproductive function. Historically, minipuberty has been considered a passive response triggered by the withdrawal of placental steroids at birth.

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Spermatogenesis is the process of generation of male reproductive cells from spermatogonial stem cells in the seminiferous epithelium of the testis. During spermatogenesis, key spermatogenic events such as stem cell self-renewal and commitment to meiosis, meiotic recombination, meiotic sex chromosome inactivation, followed by cellular and chromatin remodeling of elongating spermatids occur, leading to sperm cell production. All the mentioned events are at least partially controlled by the epigenetic modifications of DNA and histones.

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