Publications by authors named "Alzhraa S Abbas"
Article Synopsis
- Recent research suggests that endovascular therapy (EVT) may be a viable alternative to traditional anticoagulation treatments for cerebral sinus venous thrombosis (CSVT).
- A systematic review of 38 studies involving 682 patients showed high rates of favorable outcomes, with 82.6% achieving a modified Rankin Scale score of 0-2 and a 60.9% rate of complete recanalization.
- The study also highlighted a relatively low mortality rate of 6.7% and minimal new hematoma formation, indicating that EVT has a promising safety profile, but further studies are needed for conclusive results.
Article Synopsis
- Ischemic stroke, a major cause of death, highlights the need for effective detection methods like echocardiography and emerging alternatives such as cardiac CT (CCT) to identify potential cardiac sources of stroke.
- A systematic review and meta-analysis of 43 studies, involving 9,552 patients, was conducted to compare the effectiveness of CCT against the traditional echocardiography (specifically TEE) in detecting intracardiac thrombus.
- The analysis found that CCT demonstrated high sensitivity (98.38%) and specificity (96.0%) for thrombus detection, with the best results coming from delayed-phase, electrocardiogram-gated CCT, while early-phase, nongated CCT had slightly
Article Synopsis
- Endovascular thrombectomy (EVT) is the main treatment for acute ischemic stroke due to large-vessel blockage, but there’s ongoing debate about the best blood pressure control after the procedure.
- This study aimed to compare the effects of different systolic blood pressure targets on patient outcomes, mortality, and complications after EVT in ischemic stroke patients.
- A systematic review of four randomized clinical trials involving 1,571 patients found that those with intensive blood pressure control had lower rates of functional independence after the procedure, though other complications showed no significant difference.
Objective: To assess the role of net water uptake (NWU) in predicting outcomes in acute ischemic stroke (AIS) patients.
Methods: A systematic review and meta-analysis were performed, adhering to established guidelines. The search covered PubMed, Scopus, Web of Science, and Embase databases until July 1, 2023.
Health-related factors can impact aviation safety. This study investigated the published, historical aviation accidents that have been investigated by the U.S.
View Article and Find Full Text PDFBackground: The Woven Endo-Bridge (WEB) device revolutionized the treatment of wide-necked bifurcation aneurysms by intrasaccular flow diversion. The latest advancement is the WEB-17 system, offering greater flexibility with fewer wires, enabling treatment of smaller distal aneurysms using smaller microcatheters than the WEB-21 system.
Methods: We conducted a systematic review following preferred reporting items for systematic reviews and meta-analyses guidelines, analyzing data from seven retrospective cohort studies involving 483 aneurysms treated with the WEB-17 device.
Background: Sensitivity and specificity are characteristics of a diagnostic test and are not expected to change as the prevalence of the target condition changes. We sought to evaluate the association between prevalence and changes in sensitivity and specificity.
Methods: We retrieved data from meta-analyses of diagnostic test accuracy published in the Cochrane Database of Systematic Reviews (2003-2020).
Traumatic brain injury (TBI) places a heavy load on healthcare systems worldwide. Despite significant advancements in care, the TBI-related mortality is 30-50% and in most cases involves adolescents or young adults. Previous literature has suggested that neutrophil-to-lymphocyte ratio (NLR) may serve as a sensitive biomarker in predicting clinical outcomes following TBI.
View Article and Find Full Text PDFBackground: Stroke has been linked to a lack of physical activity; however, the extent of the association between inactive lifestyles and stroke risk has yet to be characterized across large populations.
Purpose: This study aimed to explore the association between activity-related behaviors and stroke incidence.
Methods: Data from 1999 to 2018 waves of the concurrent cross-sectional National Health and Nutrition Examination Survey (NHANES) were extracted.
Objective: Recent studies suggest that the clinical course and outcomes of patients with coronavirus disease 2019 (COVID-19) and myasthenia gravis (MG) are highly variable. We performed a systematic review of the relevant literature with a key aim to assess the outcomes of invasive ventilation, mortality, and hospital length of stay (HLoS) for patients presenting with MG and COVID-19.
Methods: We searched the PubMed, Scopus, Web of Science, and MedRxiv databases for original articles that reported patients with MG and COVID-19.
Parkinson's disease (PD) patients who contracted Coronavirus disease 2019 (Covid-19) had a decline in motor functions; nevertheless, there is limited evidence on whether PD patients have a higher risk for contracting Covid-19 or have worse outcomes. This is the first systematic review and meta-analysis to review the impact of PD on the prognosis of Covid-19 patients. We performed a systematic search through seven electronic databases under the recommendations of the Preferred Reporting Items for Systematic Review and Meta-analyses statement (PRISMA) guidelines.
View Article and Find Full Text PDFAmlodipine as adjuvant therapy to current chelating agents for reducing iron overload in thalassaemia major: a systematic review, meta-analysis and simulation of future studies.
Vox Sang
September 2021
Background And Objectives: Iron overload in thalassaemia is a crucial prognostic factor and a major cause of death due to heart failure or arrhythmia. Therefore, previous research has recommended amlodipine as an auxiliary treatment to current chelating agents for reducing iron overload in thalassaemia patients.
Materials And Methods: A systematic review and meta-analysis of the results of three randomized clinical trials evaluating the use of amlodipine in thalassaemia patients through 12 databases were carried out.
: To examine the safety and efficacy of hyeprimmunoglobulin therapy on vertical transmission of congenital cytomegalovirus (CCMV).: We searched nine databases for studies investigating the effect of Hyperimmunoglobulin among pregnant women with CMV.: Of total eight studies, the pooled prevalence of CCMV was 36.
View Article and Find Full Text PDFBackground: Malignant ependymomas are rare cancerous tumors that are associated with increased morbidity and mortality in the affected patients. Lately, there has been a lot of controversy about the correct way to manage and predict the survival outcome of these patients. We aim in this retrospective cohort study to develop novel nomograms that can better predict the overall survival (OS) and cancer-specific survival (CSS) of these patients.
View Article and Find Full Text PDFPurpose: This study aimed to provide an updated overview of primary central lymphoma (PCL) using a large cohort of 33 years. That being said, we attempted to examine the patient demographics, management plans and their outcome, causes of death and the time trends in overall incidence and mortality rates of these patients.
Methods: We conducted a retrospective cohort study using the Surveillance, Epidemiology, and End Results (SEER) database between 1983 and 2016.
Background: Sarcoidosis with cardiovascular involvement is critical and is associated with morbidity and mortality of the affected patients, if not properly managed. In this systematic review and meta-analysis, we aimed to review the available literature to find the prevalence of cardiovascular comorbidities and their association with sarcoidosis.
Methods: An electronic search was conducted through nine databases for articles reporting cardiovascular comorbidities in sarcoidosis patients.
Background: Kinesio tape is an elastic therapeutic tape used for treating sports injuries and various other disorders. A systematic review and network meta-analysis approach was used to synthesise all related evidence on the clinical effectiveness of kinesio taping for the treatment of shoulder pain.
Methods: A literature search was performed using 10 major databases.
There is a need for improved treatment of patients with chronic hepatitis B (CHB). We reviewed the literature to explore the efficacy of HB vaccines alone or in combination therapy (CT) with antiviral drugs in CHB patients and to meta-analyze data from randomized controlled trials. We conducted a systematic search in ten databases.
View Article and Find Full Text PDFBronchial asthma is one of the most common chronic inflammatory diseases. Complementary and alternative medicine is increasingly used for treating bronchial asthma. Ten electronic databases were searched to investigate whether honey alone or in combination with other ingredients can be considered as the potential treatment for bronchial asthma.
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