Publications by authors named "Alysson Marlin"
Article Synopsis
- Gut microbiota imbalances (dysbiosis) are linked to metabolic issues like obesity and liver problems, but how they affect these disorders is not fully understood.* -
- Transferring gut bacteria from obese mice to healthy mice reduced liver glucose production and altered gut microbiota, suggesting a connection between gut bacteria and metabolic function.* -
- The study shows that obese gut bacteria can negatively impact liver metabolism when exposed to a high-fat diet, while lean gut bacteria don’t have the same effect, offering insights into metabolic disease origins.*
Apelin is a bioactive peptide involved in the control of energy metabolism. In the hypothalamus, chronic exposure to high levels of apelin is associated with an increase in hepatic glucose production, and then contributes to the onset of type 2 diabetes. However, the molecular mechanisms behind deleterious effects of chronic apelin in the brain and consequences on energy expenditure and thermogenesis are currently unknown.
View Article and Find Full Text PDFGlucosensing in the gastrointestinal tract: Impact on glucose metabolism.
Am J Physiol Gastrointest Liver Physiol
May 2016
The gastrointestinal tract is an important interface of exchange between ingested food and the body. Glucose is one of the major dietary sources of energy. All along the gastrointestinal tube, e.
View Article and Find Full Text PDFObjective: The gut-brain axis is considered as a major regulatory checkpoint in the control of glucose homeostasis. The detection of nutrients and/or hormones in the duodenum informs the hypothalamus of the host's nutritional state. This process may occur via hypothalamic neurons modulating central release of nitric oxide (NO), which in turn controls glucose entry into tissues.
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