Lesion and lesion network localization of dysnomia after epilepsy surgery.

Temporal lobe (TL) epilepsy surgery is an effective treatment option for patients with drug-resistant epilepsy. However, neurosurgery poses a risk for cognitive deficits - up to one third of patients have a decline in naming ability following TL surgery. In this study, we aimed to better understand the neural correlates associated with reduced naming performance after TL surgery, with the goal of informing surgical planning strategies to mitigate the risk of dysnomia.

Anterolateral temporal lobe localization of dysnomia after temporal lobe epilepsy surgery.

Objectives: To evaluate what factors influence naming ability after temporal lobectomy in patients with drug-resistant epilepsy.

Methods: 85 participants with drug-resistant epilepsy who underwent temporal lobe (TL) resective surgery were retrospectively identified (49 left TL and 36 right TL). Naming ability was assessed before and >3 months post-surgery using the Boston Naming Test (BNT).

Implications of age at lesion onset for neuropsychological outcomes: A systematic review focusing on focal brain lesions.

Theories of the relation between age at lesion onset and outcomes posit different views of the young brain: resilient and plastic (i.e., the so-called "Kennard Principle"), or vulnerable (i.

Academic skills after brain injury: A lifespan perspective.

Objectives: This study investigated academic skills outcomes after brain injury and identified the influence of age and injury factors across the lifespan.

Method: Our sample included 651 participants with focal brain lesions. Math, reading, and spelling data from the Wide Range Achievement Test (WRAT) were used as the academic skills outcomes.

A human amygdala site that inhibits respiration and elicits apnea in pediatric epilepsy.

BACKGROUNDSeizure-induced inhibition of respiration plays a critical role in sudden unexpected death in epilepsy (SUDEP). However, the mechanisms underlying seizure-induced central apnea in pediatric epilepsy are unknown.METHODSWe studied 8 pediatric patients with intractable epilepsy undergoing intracranial electroencephalography.