Publications by authors named "Alyssa Sim"

Article Synopsis
  • The study examines the link between liver disease type (alcohol-related vs non-alcohol-related) and 6-week mortality following acute variceal bleeding (AVB) in patients with cirrhosis.
  • Researchers analyzed data from two large cohorts in the U.S. and Singapore, including 1,349 patients, and found that non-ALD patients had a significantly higher risk of mortality compared to ALD patients.
  • Incorporating the etiology of cirrhosis into existing mortality prediction models improved accuracy, highlighting the importance of considering the type of liver disease for patient care.
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An HCV elimination program aims to diagnose more than 90% of Chronic HCV cases. We critically evaluated the performance of a point-of-care test (POCT) using an HCV Rapid Antibody Test. PWID from 4 Halfway Houses (HWH) in Singapore were recruited from March 2022 to April 2023.

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Background And Aims: Acute variceal bleeding (AVB) is a major complication in patients with cirrhosis. Using a nationwide AVB audit, we performed a nested cohort study to determine whether full adherence to the AVB quality indicator (QI) improves clinical outcomes in patients with cirrhosis and AVB.

Approach And Results: We assessed real-world adherence to AVB QI among patients with cirrhosis admitted for AVB in all public hospitals in Singapore between January 2015 and December 2020.

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Background: Drug-coated balloons (DCB) have been used to treat de novo small vessel coronary disease (SVD), with promising results and shorter dual antiplatelet therapy (DAPT) duration compared to drug-eluting stents (DES). We compared safety and effectiveness of the two treatments at 1 year.

Methods: We reviewed 3,613 angioplasty cases retrospectively from 2011 to 2013 and identified 335 patients with SVD treated with device diameter of ≤2.

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