Publications by Alyssa S Mendelowitz

Publications by authors named "Alyssa S Mendelowitz"

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Efficiently targeting neuroblastoma with the combination of anti-ROR1 CAR NK cells and N-803 and in NB xenografts.

Yaya Chu Gaurav Nayyar Meijuan Tian Dean A Lee Mehmet F Ozkaynak Alyssa S Mendelowitz

Mol Ther Oncol

June 2024

The prognosis for children with recurrent and/or refractory neuroblastoma (NB) is dismal. The receptor tyrosine kinase-like orphan receptor 1 (ROR1), which is highly expressed on the surface of NB cells, provides a potential target for novel immunotherapeutics. Anti-ROR1 chimeric antigen receptor engineered expanded peripheral blood natural killer (anti-ROR1 CAR exPBNK) cells represent this approach.

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