Publications by authors named "Alyssa K Phillips"

Both genetics and lifestyle contribute to type 2 diabetes (T2D), a condition of elevated circulating glucose induced by a collection of metabolic defects including peripheral insulin resistance, elevated hepatic glucose output, and impaired pancreatic insulin secretion. Because the prevalence of T2D and its modifiable risk factors (overweight/obesity, dyslipidemia, hypertension, and physical inactivity) have been increasing in recent decades, there has been growing interest in lifestyle interventions that target T2D management and prevention. Although it is increasingly recognized that lifestyle interventions aimed at encouraging physical activity and reducing body weight can improve insulin sensitivity, nutritional contributions to T2D risk reduction are less clear.

View Article and Find Full Text PDF

The incidence of hypertriglyceridemia has grown alongside that of obesity. Statin therapy has been widely recommended for the treatment of dyslipidemias. Omega-3 (OM3) fatty acid concentrates are commonly prescribed concurrently with statins in patients with persistent hypertriglyceridemia for additional lowering of triglyceride and non-HDL cholesterol.

View Article and Find Full Text PDF

Background: Maternal anemia and several complications of pregnancy can affect fetal iron acquisition.

Aim: Because it is unknown whether the effects of demographic and maternal risk factors (RF) are summative, we examined cord iron status in newborns with multiple RF for acquiring iron deficiency.

Methods: Cord blood indices from healthy control newborns with and without RF for newborn or infant iron deficiency were studied.

View Article and Find Full Text PDF

Background: Maternal minority status is a risk factor for iron deficiency in infancy and pregnancy. Because language and cultural differences may limit research participation, a prospective study examining iron deficiency included maternal minority status as an inclusionary criterion. Cognizant of potential barriers to recruitment, goals were to quantify eligible Latina enrollees and refusals, examine participation barriers, and devise possible solutions.

View Article and Find Full Text PDF