2-Aminopyridine Analogs Inhibit Both Enzymes of the Glyoxylate Shunt in .

is an opportunistic pathogen responsible for many hospital-acquired infections. can thrive in diverse infection scenarios by rewiring its central metabolism. An example of this is the production of biomass from C nutrient sources such as acetate via the glyoxylate shunt when glucose is not available.

Structural and Functional Characterization of Malate Synthase G from Opportunistic Pathogen Pseudomonas aeruginosa.

Pseudomonas aeruginosa is an opportunistic human pathogen recognized as a critical threat by the World Health Organization because of the dwindling number of effective therapies available to treat infections. Over the past decade, it has become apparent that the glyoxylate shunt plays a vital role in sustaining P. aeruginosa during infection scenarios.