2-hydroxy-1,4-naphthoquinones with 3-alkyldiarylether groups: synthesis and inhibitory activity.

In 1948, the synthesis and activity of 2-hydroxy-1,4-naphthoquinones containing 3-alkyldiarylether side chains was reported. The synthesis of five related compounds, designed to be more metabolically stable, was pursued. The compounds were synthesized using a radical alkylation reaction with naphthoquinones.