Publications by authors named "Alysha G Colon"
Background: Relative enlargement of the pulmonary artery (PA) on chest CT imaging is associated with respiratory exacerbations in patients with COPD or cystic fibrosis. We sought to determine whether similar findings were present in patients with asthma and whether these findings were explained by differences in ventricular size.
Methods: We measured the PA and aorta diameters in 233 individuals from the Severe Asthma Research Program III cohort.
Rationale: Loss of the peripheral pulmonary vasculature, termed vascular pruning, is associated with disease severity in patients with chronic obstructive pulmonary disease.
Objectives: To determine if pulmonary vascular pruning is associated with asthma severity and exacerbations.
Methods: We measured the total pulmonary blood vessel volume (TBV) and the blood vessel volume of vessels less than 5 mm in cross-sectional area (BV5) and of vessels less than 10 mm (BV10) in cross-sectional area on noncontrast computed tomographic scans of participants from the Severe Asthma Research Program.