Publications by authors named "Alyse Peters"
Article Synopsis
- Metal oxide nanoparticles (MONPs), like ZnO and CuO, are commonly used in agriculture but their effects on human health, especially in cancer cells, are not well understood.
- In experiments with thyroid cancer cells, exposure to CuO and ZnO significantly reduced cell viability, which was linked to increased apoptosis rather than oxidative stress.
- RNA sequencing revealed that various signaling pathways related to inflammation and cell adhesion were altered, indicating that different cellular mechanisms contribute to cell death caused by these nanoparticles.
Next-generation sequencing (NGS) technology has revolutionized sequence-based research. In recent years, high-throughput sequencing has become the method of choice in studying the toxicity of chemical agents through observing and measuring changes in transcript levels. Engineered nanomaterial (ENM)-toxicity has become a major field of research and has adopted microarray and newer RNA-Seq methods.
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