Publications by authors named "Alyona Boltanova"
Article Synopsis
- Primary biliary cholangitis (PBC) is a liver and immune system condition, and a study investigated the effects of transplanting autologous bone marrow-derived mononuclear cells (BM-MNCs) in affected patients.
- Sixteen PBC patients underwent BM-MNC harvesting and transplantation between 2017 and 2022, with monitoring of liver function and immune cell changes over time using statistical analyses.
- The results showed significant improvements in liver function tests and notable changes in immune cell populations, suggesting that BM-MNC transplantation could be a promising therapeutic approach for managing PBC.
Objectives: Our goal was to determine levels of sex hormones in men with type 1 diabetes mellitus and type 2 diabetes mellitus after autologous mesenchymal stem cell transplant.
Materials And Methods: We examined 10 male patients (32-56 years old) with type 1 diabetes mellitus and type 2 diabetes mellitus, whom we subsequently divided into 2 groups and examined. Group 1 comprised 5 male patients who received autologous mesenchymal stem cell transplant (cells were obtained from patient's iliac crest and cultured for 3-4 weeks) by intravenous infusion.
The diagnosis of Celiac Disease (CD) is first based on the positivity for specific serological markers. The CytoBead CeliAK immunoassay simultaneously measures antibodies (IgA) directed to tissue transglutaminase (tTG), endomysium (EMA), and deamidated gliadin (DG), in addition to providing a control for total IgA levels. The aim of this study is to assess the reliability of this multiplex assay to detect anti-tTG IgA positive patients, compared with a conventional single-parameter enzyme-linked immunosorbent assay (ELISA).
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