Assessment of human disc degeneration and proteoglycan content using T1rho-weighted magnetic resonance imaging.

Study Design: T1rho relaxation was quantified and correlated with intervertebral disc degeneration and proteoglycan content in cadaveric human lumbar spine tissue.

Objective: To show the use of T1rho-weighted magnetic resonance imaging (MRI) for the assessment of degeneration and proteoglycan content in the human intervertebral disc.

Summary Of Background Data: Loss of proteoglycan in the nucleus pulposus occurs during early degeneration.

Differences between middle cerebral artery blood velocity waveforms of young and postmenopausal women.

Objective: We characterized middle cerebral artery (MCA) blood flow velocity waveforms measured by transcranial Doppler ultrasonography in premenopausal (26.6 +/- 6.1 years, mean +/- SD) and postmenopausal (54.