Publications by authors named "Alyaa M Ajabnoor"

Aims: To compare the predictive performance of CHADS-VASc and HAS-BLED scores in atrial fibrillation (AF) patients with and without cancer.

Methods And Results: Using data from the Clinical Practice Research Datalink in England, we performed a retrospective cohort study of patients with new diagnoses of AF from 2009 to 2019. Cancer was defined as history of breast, prostate, colorectal, lung, or haematological cancer.

View Article and Find Full Text PDF
Article Synopsis
  • Anticoagulation therapy in patients with atrial fibrillation (AF) and cancer is complex due to the balance between stroke risk and bleeding, with significant variations in prescribing practices observed.
  • A study analyzed 177,065 AF patients and found that 11.7% had cancer, and those patients were less likely to receive oral anticoagulants (OAC), especially those with hematological and lung cancers.
  • The results indicate that elderly patients (≥85 years) had the lowest rates of OAC prescribing, highlighting a need for more research on the benefits of anticoagulation in this demographic and specific cancer types.
View Article and Find Full Text PDF

Background: The association between cancer and stroke or bleeding outcomes in atrial fibrillation is unclear. We sought to examine how certain types of cancer influence the balance between stroke and bleeding risk in patients with nonvalvular atrial fibrillation (NVAF).

Methods And Results: We estimated stroke and bleeding risk among adult patients with NVAF and certain types of cancer (breast, prostate, colorectal, lung, and hematological cancer) from 2009 to 2019 based on data from the UK Clinical Practice Research Datalink GOLD and Aurum databases.

View Article and Find Full Text PDF

Background: Atrial fibrillation (AF) is an important risk factor for ischaemic stroke, and AF incidence is expected to increase. Guidelines recommend using oral anticoagulants (OACs) to prevent the development of stroke. However, studies have reported the frequent underuse of OACs in AF patients.

View Article and Find Full Text PDF

Pharmacist prescribing is being increasingly undertaken to better use their skills and reduce the workload of existing prescribers such as doctors, often using formal processes to legitimate these activities. In developing countries like Saudi Arabia, however, pharmacists' prescribing remains informal with no legislation or formal training and there is a lack of research and understanding into such practices. Therefore, we aimed to describe current pharmacist prescribing practices in Saudi Arabia and explore pharmacists' views about pharmacists' prescribing.

View Article and Find Full Text PDF