Public Health.

Background: Working conditions and contexts may influence the development of Alzheimer's Disease and related dementias (ADRD), exposing individuals to modifiable risk factors across their life. Measurement of ADRD pathology at autopsy provides a gold standard outcome for evaluating the effects of lifetime exposures, but approaches to quantify ante-mortem work exposures are limited. Here we describe a new method to retrospectively capture occupational histories by systematically extracting occupational information using archival public records- i.

Deriving life-course residential histories in brain bank cohorts: A feasibility study.

Introduction: The exposome is theorized to interact with biological mechanisms to influence risk for Alzheimer's disease but is not well-integrated into existing Alzheimer's Disease Research Center (ADRC) brain bank data collection.

Methods: We apply public data tracing, an iterative, dual abstraction and validation process rooted in rigorous historic archival methods, to develop life-course residential histories for 1254 ADRC decedents.

Results: The median percentage of the life course with an address is 78.

The association between attitudes and the provision of medications for opioid use disorder (MOUD) in United States jails.

Background: Opioid use disorder is prevalent among individuals who are incarcerated, yet medications for opioid use disorder (MOUD) are not widely available in United States jails and prisons. Negative staff attitudes across the criminal legal system may prevent MOUD from being provided. We sought to determine if staff attitudes are associated with the provision of MOUD in prisons or jails.