Publications by authors named "Aly A"

In this investigation, a novel alginate complex was developed for the selective separation of molybdenum (Mo(VI)) ions from some rare earth elements (REEs). In this regard, alginate as a natural polysaccharide was impregnated and modified with 2-hydroxy-5-nonylacetophenone oxime (Lix-84) and characterized using FT-IR, TGA/DTA and SEM-EDX. The relation between medium acidity, adsorption kinetics, sorbent dose, isotherm models, temperature and Mo(VI) recovery was investigated.

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Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, which is still missing effective therapeutic strategies. Although manipulation of neuronal excitability has been tested in murine and human ALS models, it is still under debate whether neuronal activity might represent a valid target for efficient therapies. In this study, we exploited a combination of transcriptomics, proteomics, optogenetics and pharmacological approaches to investigate the activity-related pathological features of iPSC-derived C9orf72-mutant motoneurons (MN).

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Although most of the early research studies on fractional-order systems were based on the Caputo or Riemann-Liouville fractional-order derivatives, it has recently been proven that these methods have some drawbacks. For instance, kernels of these methods have a singularity that occurs at the endpoint of an interval of definition. Thus, to overcome this issue, several new definitions of fractional derivatives have been introduced.

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Backgrounds: Publicly funded obesity surgery remains underfunded in Australia. One barrier to expansion is the perception that perioperative care requires critical care facilities. This study evaluates the effectiveness of patient selection criteria in avoiding unplanned patient transfer and adverse outcomes in obesity surgery performed at a facility without a high-dependency unit/intensive care unit (HDU/ICU).

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In this paper, we investigate the fractional epidemic mathematical model and dynamics of COVID-19. The Wuhan city of China is considered as the origin of the corona virus. The novel corona virus is continuously spread its range of effectiveness in nearly all corners of the world.

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Effective confinement of light and sound is achieved through a one-dimensional phoxonic crystal (PxC) cavity. In particular, co-localization of gigahertz phonons and infrared photons in a cavity created by introducing a defect inside a multilayer PxC has been performed. The incident elastic waves can control the refractive index variation of the dual phononic-photonic cavity layer.

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Purpose: Cushingoid features are occasionally encountered in infants after pediatric cataract surgery. The aim of this study is to evaluate whether the use of topical glucocorticoids (GCs) following congenital cataract surgery can result in endogenous adrenal suppression and/or systemic side effects similar to those seen with systemic steroids.

Methods: A prospective study was performed on 20 infants with bilateral congenital cataract.

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Aim: Therapeutic choices for cancer patients include many combinations of therapeutic protocols. The present study aimed to investigate and discuss the combined effects of magnetic field and chemotherapy treatment on Ehrlich tumor-induced growth in Swiss albino mice. The benefits of both treatments are discussed and interpreted.

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Ischemic mitral regurgitation (IMR) is a prevalent cardiac disease associated with substantial morbidity and mortality. Contemporary surgical treatments continue to have limited long-term success, in part due to the complex and multi-factorial nature of IMR. There is thus a need to better understand IMR etiology to guide optimal patient specific treatments.

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There is little information on the acute cerebrovascular complications of coronavirus disease 2019 (COVID-19) in Egypt. The aim of this study was to estimate the proportion of acute cerebrovascular disease (CVD) among COVID-19 patients and evaluate their clinical and radiological characteristics in comparison with non-COVID-19 CVD. In a retrospective study, COVID-19 patients whom presented with CVD in Assiut and Aswan University Hospitals were compared with non-COVID-19, CVD patients, admitted to Qena University Hospital, prior to the pandemic.

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The development of a scaffold matrix to promote wound healing is a critical requirement to improve the health care system. For this purpose, electrospun scaffolds of polycaprolactone (PCL) have been encapsulated with hydroxyapatite (HAP) doped with different contributions Ag ions. The obtained scaffolds have been investigated by XRD, FTIR and FESEM.

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Background: In vivo characterization of mitral valve dynamics relies on image analysis algorithms that accurately reconstruct valve morphology and motion from clinical images. The goal of such algorithms is to provide patient-specific descriptions of both competent and regurgitant mitral valves, which can be used as input to biomechanical analyses and provide insights into the pathophysiology of diseases like ischemic mitral regurgitation (IMR).

Objective: The goal is to generate accurate image-based representations of valve dynamics that visually and quantitatively capture normal and pathological valve function.

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Atraumatic splenic rupture (ASR) is a rare complication of acute pancreatitis with high mortality and morbidity rates. We present a case of a 63-year-old woman with a history of hypertension, presenting with acute pancreatitis who subsequently developed a splenic rupture requiring a laparotomy and splenectomy. ASR is a rare but life-threatening complication requiring prompt recognition and management and should be considered in patient with pancreatitis who develops sudden haemodynamic compromise and worsening anaemia.

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is part of the commensal flora of the oral cavity, frequently associated with periodontal infections. We describe the case of a 49-year-old woman, on immunsuppressive therapy for multiple sclerosis, who presented with a 3-month history of debilitating back pain. She had a recent episode of periodontitis, and was under regular dental review.

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Background: Quinine (QU) as an anti-malarial drug induces alterations in testicular tissue. Toxic effects of monosodium glutamate (MSG) on the male reproductive system have been recognized.

Objective: To investigate the impact of MSG administration on the intensity of gonadotoxicity of QU.

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In this paper, nanoscale pores in silicon layers are exploited to model and optimize a one-dimensional hybrid graphene-porous silicon photonic crystal biosensor. The physical nature of the proposed sensor is based on Tamm resonance. The transfer matrix method is applied to detect the change of the index of refraction in an aqueous solution.

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Introduction: Thumb metacarpophalangeal joint instability can have a considerable functional impairment. Acute injuries are usually overlooked in children due to the high pain threshold and the presence of ligamentous laxity. Chronicity of the injury results in failure of conservative treatment.

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Echocardiogram (echo) is a commonly used noninvasive modality for the diagnosis of bronchopulmonary dysplasia associated pulmonary hypertension (BPD-PH). Though not considered the gold standard for the diagnosis of BPD-PH, it is an extremely valuable tool in the neonatal and pediatric population, especially when cardiac catheterization is not feasible. In addition to the traditional echo parameters that are used to assess the presence of BPD-PH, much attention has been recently placed on newer bedside echo measures, the so-called functional echo parameters, to aid and assist in the diagnosis.

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There is a continuous need in drug development approach for synthetic anticancer analogues with new therapeutic targets to diminish chemotherapeutic resistance of cancer cells. This study presents new group of synthetic thienopyrimidine analogues (1-9) aims as mGluR-1 inhibitors with anticancer activity. In-vitro antiproliferative assessment was carried out using viability assay against cancer cell lines (MCF-7, A-549 and PC-3) compared to WI-38 normal cell line.

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Purpose: To assess the reliability and efficacy of the modified oblique high tibial osteotomy for correction of complex deformity in adolescent tibia vara.

Methods: A total of 19 patients (25 legs) with adolescent tibia vara were enrolled in this study. There were 16 male (84.

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Background: COVID-19 can be accompanied by acute neurological complications of both central and peripheral nervous systems (CNS and PNS). In this study, we estimate the frequency of such complications among hospital inpatients with COVID-19 in Assiut and Aswan university hospitals.

Materials And Methods: We screened all patients with suspected COVID-19 admitted from 1 June to 10 August 2020 to the university hospitals of Assiut and Aswan in Upper Egypt.

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A combination of nanostructured zinc oxide (ZnO) or graphene oxide or both of them with cellulose acetate (CA) enhances a new functionality of nanofibers aiming to improve bio-composite materials for wound healing application. The obtained nanofibers have been investigated using XRD, FTIR, and FESEM. It was observed that the maximum height of the roughness increased from 253 to 651.

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Distal radio-ulnar joint (DRUJ) injuries are under-reported in the paediatric population. No single study has discussed methods of DRUJ reconstruction in immature patients with chronic instability. We present a physeal sparing ligamentoplasty for chronic DRUJ instability and describe the outcomes in two patients.

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Sodium-glucose cotransporter 2 (SGLT2) inhibitors, which are used for treatment of type 2 diabetes, are associated with risk of urogenital infections. FDA issued a black box warning about multiple case reports of Fournier's gangrene (FG) observed in patients taking SGLT2 inhibitors. FG is a type of necrotising fasciitis that occurs in the anogenital area.

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Advances in imaging have resulted in more frequent reporting of primitive right atrial structures which can sometimes mimic cardiac tumors in prenatal ultrasound. Prominent crista terminalis and Chiari network are examples of these structures. We describe two cases of pregnant women referred to the fetal cardiology clinic for fetal echocardiography for right atrial masses seen on prenatal ultrasound suspicious of tuberous sclerosis.

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