Expression of Interleukin-17, Tumor Necrosis Factor-Alpha, and Matrix Metalloproteinase-8 in Patients with Chronic Peri-Implant Mucositis.

BACKGROUND The present study aimed to evaluate whether non-surgical treatment interferes with clinical parameters and local patterns of osteo-immunoinflammatory mediators (IL-17 and TNF-alpha) and matrix metalloproteinase-8 (MMP-8) that are found in peri-implant crevicular fluid (PICF) and biofilms during the progression of peri-implant mucositis. MATERIAL AND METHODS We selected 30 patients with peri-implant caused mucositis before (MP) and after treatment (TP) and 30 healthy people (HP) for the analysis of IL-17, TNF-alpha cytokine, and MMP-8 production in PICF and for analysis of colonization dynamics of periodontopathogenic bacteria in supra- and subgingival plaque samples. The levels of IL-17 and MMP-8 concentrations in samples were assayed by enzymatic immunosorbent assay (ELISA) and TNF-alpha levels were determined by enzyme amplified sensitivity immunoassay (EASIA) method in PICF.

Interleukin-10 and Interleukin-1β Cytokines Expression in Leukocytes of Patients with Chronic Peri-Mucositis.

BACKGROUND The purpose of the present research is to analyze the effect of polyphenols and flavonoids substrat (PFS) from plants Calendula officinalis, Salvia fruticosa, Achillea millefolium, and propolis as immunomodulatory in the production of interleukin (IL)-1ß and IL-10 in peripheral blood leukocytes medium (PBLM) in patients who were diagnosed with mucositis of peri-implant tissue compared to patients with healthy implant tissue. It was hypothesized that IL-1ß and IL-10 contribute to the inflammation processes noticed in the diseases of peri-implant tissues. MATERIAL AND METHODS Sixty non-smoking patients were included in this study: patients with healthy implants (HP group) and patients with peri-implant mucositis (MP group).

The Influence of Porphyromonas Gingivalis Bacterium Causing Periodontal Disease on the Pathogenesis of Rheumatoid Arthritis: Systematic Review of Literature.

Periodontal pathologies are highly widespread throughout the world. Epidemiological studies have shown that as much as 1% of the population is suffering from periodontal disease. In recent years, there has been a growing number of studies linking these diseases with autoimmune diseases, especially with rheumatoid arthritis.

The comparison of cement- and screw-retained crowns from technical and biological points of view.

Objective: The aim of this review was to evaluate the most common complications in implant prosthodontics with porcelain-fused-to-metal crowns, to evaluate the influence of biomechanical properties on fractures and cracks of veneered porcelain, and to compare the effects of crowns with different connections on soft tissues.

Material And Methods: A search of literature in the English language between 2009 and 2015 was conducted using the following databases: Medline via PubMed, Science Direct, Wiley online library, Taylor& Francis, and Cochrane library. In total, 10 studies that met the inclusion criteria were found.

Host responses to Candida albicans. A review.

Candida albicans is the most prevalent human fungal pathogen, that is component of the commensal microbial flora of the mouth. Under certain conditions, C. albicans can cause severe diseases, septicaemia, and death.

Peripheral Blood Leukocytes Interleukin-1 Beta (IL-1β) Cytokine Hyper-Reactivity in Chronic Periodontitis.

BACKGROUND Levels of pro-inflammatory cytokine (IL-1β) released by peripheral blood leukocyte medium (PBLM), isolated from chronic periodontitis patients (P) before therapy and matched to controls, were determined in the presence or absence of non-opsonized Escherichia coli and Staphylococcus aureus. MATERIAL AND METHODS In this investigation, 26 patients with untreated, severe, generalized, chronic periodontitis and 26 healthy subjects (H) were enrolled. Periodontal status was assessed by measuring bleeding on probing (BOP), clinical attachment loss (CAL), probing pocket depth (PPD), and Ramfjord index (PDI).

Effect of Supragingival Irrigation with Aerosolized 0.5% Hydrogen Peroxide on Clinical Periodontal Parameters, Markers of Systemic Inflammation, and Morphology of Gingival Tissues in Patients with Periodontitis.

BACKGROUND Various studies have shown that non-surgical periodontal treatment is correlated with reduction in clinical parameters and plasma levels of inflammatory markers. The aim of this study was to evaluate the effect of long-term weekly supragingival irrigations with aerosolized 0.5% hydrogen peroxide as maintenance therapy followed by non-surgical periodontal treatment on clinical parameters, plasma levels of inflammatory markers, and morphological changes in gingival tissues of patients with periodontitis.

Candida albicans importance to denture wearers. A literature review.

Opportunistic oral fungal infections have spred, especially in denture wearers. Denture stomatitis is a common inflammatory reaction, multifactorial etiology, which is usually associated with Candida species, particularly Candida albicans, due to its high virulence, ability to adhere and form biofilms on oral cavity tissues and denture surfaces. This article highlights the pathogenesis, clinical presentation, and management strategies of Candida-associated denture stomatitis commonly encountered in dental practice.

A revised approach of human mastication function rehabilitation through monotypical mastication analysis.

Objective: The aim of the simulation was to find the forcing laws, which provide the close-to reality mastication motions of the components of the system and to investigate the contact zones, interaction forces and their action points as they vary in time. The loss of one or few elements of the mastication system can be restored without significant violations of the overall function provided the general correlations among the mastication system elements, which were influenced during the evolutionary development, have been determined in advance.

Materials And Methods: We present an approach based on the computer simulation of mastication biomechanics on the basis of finite element (FE) models.

The relationship between unilateral mandibular angle fracture and temporomandibular joint function.

PURPOSE. Aim of this study was to analyze relation of occlusal correction and alterations of temporomandibular joint function during treatment of unilateral mandibular fractures. MATERIALS AND METHODS.

Relationship of clinical and microbiological variables in patients with type 1 diabetes mellitus and periodontitis.

Background: The aim of the study was to analyze how metabolic control of type 1 diabetes is related to clinical and microbiological periodontal parameters.

Material And Methods: The study involved 56 subjects aged from 19 to 50 years divided into 2 groups: healthy subjects (the H group), and diabetic (type 1 diabetes) patients with chronic untreated generalized periodontitis (the DM group). The glycosylated hemoglobin value (HbA1c) was determined using the UniCel DxC 800 SYNCHRON System (Beckman Coulter, USA), and the concentration in blood was measured by the turbidimetric immunoinhibition method.

Viability changes: microbiological analysis of dental casts.

Background: This study evaluated the survival of the most prevalent oral bacteria and fungi (Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli, and Candida albicans) in dental casts, and compared changes in the amounts of these microorganisms at different time intervals to determine how long dental casts may pose threat to the health of dental personnel and patients.

Material And Methods: When manufacturing the casts, regular water was replaced with sterile distilled water, where suspensions of the studied bacteria or the fungus at certain concentrations were prepared. When the dental casts were fully set (solidified), plaster shavings were examined immediately after the contact of the studied microorganism with the plaster, as well as after 1, 2, 24, 48, 72, 96, and 120 hours.

Dynamical changes of occlusion and articulation during treatment of mandibular angle fractures.

Outcomes of mandibular fractures were stated as frequent reason of temporomandibular joint dysfunctions. The objective of this study was to evaluate dynamical changes of occlusion and articulation during treatment of mandibular angle fractures. 12 subjects with mandibular angle fractures underwent analysis of occlusion and articulation in all stages of healing.

New approach towards mini dental implants and small-diameter implants: an option for long-term prostheses.

BACKGROUND. Mini dental implants (MDI) and small diameter implants (SDI) have been extensively used as temporary or orthodontic anchorage; however there have been studies that proved their availability as a mean for long term prosthodontics. Our aim was to review the indications, advantages of MDI and SDI, and their long-term survival.

Effect of (1→3),(1→6)-β-glucan on in vitro production of cytokines by leukocytes of patients with periodontitis.

BACKGROUND. The aim of the study was to investigate the effect of (1→3), (1→6)-β-glucan on the production of interleukin 10 (IL-10) and tumor necrosis factor α (TNF-α) in vitro by peripheral blood leukocytes of patients with periodontitis. MATERIAL AND METHODS.

The preservation of alveolar bone ridge during tooth extraction.

Objectives: The aims were to overview healing of extraction socket, recommendations for atraumatic tooth extraction, possibilities of post extraction socket bone and soft tissues preservation, augmentation.

Materials And Methods: A search was done in Pubmed on key words in English from 1962 to December 2011. Additionally, last decades different scientific publications, books from reference list were assessed for appropriate review if relevant.

Squamous cell carcinoma of the left temporal region.

Clinical case is about squamous cell carcinoma in region of face and head. Patient was diagnosed with 6-7 cm tumor in region of temple in the left side of the face. Patient took his first medical advice after 8 years then he felt first symptoms.

Adaptation and validation of the early childhood oral health impact scale in Lithuania.

Background: The Early Childhood Oral Health Impact Scale (ECOHIS) is a parent--assessed oral health related quality of life measure developed to assess the impact of oral health problems on preschool children.

Aim: The aim of this study was to develop a Lithuanian version of the ECOHIS and evaluate its validity and reliability among preschool children in Lithuania.

Design: A lithuanian version of ECOHIS (L-ECOHIS) was developed through a forward-backword translation.

Activity of neutrophil β-glucuronidase in diabetic and nondiabetic patients with chronic generalized periodontitis and healthy subjects.

OBJECTIVE. The aim of the study was to establish the dynamics of β-glucuronidase activity in subjects suffering from type 1 diabetes and chronic untreated generalized periodontitis, subjects suffering from chronic untreated generalized periodontitis only, and control subjects not suffering from generic diseases with healthy periodontal tissue. MATERIAL AND METHODS.

Lysozyme and microbiota in relation to gingivitis and periodontitis.

Background: The aim of this study was to investigate associations between the immune component of the oral cavity, lysozyme, in gingival crevicular fluid and unstimulated saliva, and colonization dynamics of periodontopathogenic bacteria from supra- and subgingival plaque samples in patients with gingivitis or periodontitis.

Material/methods: Lysozyme in crevicular fluid and unstimulated saliva, and bacteria in supra- and subgingival plaque samples were assessed in 84 samples from 28 patients with gingivitis, 96 samples from 32 patients with periodontitis, and 72 samples from 24 donors with intact periodontium and free of internal disease. Lysozyme activity was determined spectrophotometrically.

Secretory function of neutrophilic leukocytes of the patients with periodontal diseases.

Aim of study was to examine periodontal status among 20 44 year old patients and to study the secretory function of peripheral venous blood neutrophilic leukocytes (NL) exposed to various antigens and alkaline phosphatase (AP) activity in gingival crevicular fluid (GCF) in patients suffering from gingivitis and periodontitis. Clinically were determined Russell's periodontal index (PI). Secretory function of NL affected by opsonized zymosane, non-opsonized E.