Publications by authors named "Alvin S M Chang"
Article Synopsis
- * A study reviewed 36 neonatal trials from 2015 to 2020, assessing their adherence to these reporting guidelines and extracting examples of effective outcome reporting across various categories.
- * Clear examples of successful outcome reporting were identified, intended to guide future trials in providing comprehensive data, thereby enhancing research quality and minimizing waste.
Article Synopsis
- The study aimed to evaluate how primary outcomes are reported in neonatal clinical trials, focusing on recent trials and their adherence to standardized core outcome sets.
- They assessed 36 trials from 2015 to 2020, noting that, while some aspects were well-reported (like statistical methods), there were significant gaps in reporting important details like minimal important difference and outcome assessment blinding.
- The researchers concluded that better reporting practices following existing guidelines are essential for improving the clarity and usefulness of neonatal trial results for decision-making in healthcare.
We present the revised Neonatal Resuscitation Guidelines for Singapore. The 2015 International Liaison Committee on Resuscitation Neonatal Task Force's consensus on science and treatment recommendations (2015), and guidelines from the American Heart Association and European Resuscitation Council were debated and discussed. The final recommendations of the National Resuscitation Council, Singapore, were derived after the task force had carefully reviewed the current available evidence in the literature and addressed their relevance to local clinical practice.
View Article and Find Full Text PDFBackground: Maternal antenatal transfers provide better neonatal outcomes. However, there will inevitably be some infants who require acute transport to a neonatal intensive care unit (NICU). Because of this, many institutions develop services to provide neonatal transport by specially trained health personnel.
View Article and Find Full Text PDFIntroduction: We aimed to study the profile of nonimmune hydrops fetalis (NIHF) in the local population and identify its outcomes and causes.
Methods: We carried out a retrospective review of the medical records in KK Women's and Children's hospital, a single tertiary referral centre, for pregnancies with an antenatal diagnosis of NIHF in the six-year period from 1 January 2005 to 31 December 2010.
Results: A total of 29 cases of NIHF were identified; 19 (66%) cases underwent karyotype evaluation, 17 (59%) underwent intrauterine infection screening, and all underwent antenatal thalassaemia screening.
Background: Over a 10-year period there was increasing involvement by clinicians in the generation and implementation of evidence-based practices in the neonatal intensive care unit (NICU). For two cohorts of very low birth weight (VLBW) babies admitted 10 years apart to a developing country, NICU were compared and changes occurring in process of care that might have contributed to any change in outcome were documented.
Methods: Prospective data were collected on characteristics, management and complications of all VLBW infants admitted over the same 6-month period in 1993 and 2003 and examined for changes in evidence-based practices and outcome.