Review of clinical manifestations of biochemically-advanced prostate cancer cases.

Objective: To review the pattern of initial clinical manifestation of patients who present with biochemically-advanced prostate carcinoma.

Methods: A review of 39 prostate cancer patients with initial prostate specific antigen (PSA) levels of more than 400 ng/mL (study group) and 40 patients whose initial PSA levels were between 20 and 399 ng/mL (control group) was done.

Results: The epidemiological profile and median Gleason score were similar in both groups.